ID   A0A439D6D3_9PEZI        Unreviewed;       855 AA.
AC   A0A439D6D3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=XPG-I domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EKO27_g5149 {ECO:0000313|EMBL:RWA09958.1};
OS   Xylaria grammica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Xylaria.
OX   NCBI_TaxID=363999 {ECO:0000313|EMBL:RWA09958.1, ECO:0000313|Proteomes:UP000286045};
RN   [1] {ECO:0000313|EMBL:RWA09958.1, ECO:0000313|Proteomes:UP000286045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IHI A82 {ECO:0000313|EMBL:RWA09958.1,
RC   ECO:0000313|Proteomes:UP000286045};
RA   Buettner E., Kellner H.;
RT   "Draft genome sequence of Xylaria grammica IHI A82.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWA09958.1}.
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DR   EMBL; RYZI01000133; RWA09958.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A439D6D3; -.
DR   STRING; 363999.A0A439D6D3; -.
DR   Proteomes; UP000286045; Unassembled WGS sequence.
DR   GO; GO:0008821; F:crossover junction DNA endonuclease activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR   CDD; cd09906; H3TH_YEN1; 1.
DR   CDD; cd09870; PIN_YEN1; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR041177; GEN1_C.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   InterPro; IPR037316; Yen1_H3TH.
DR   PANTHER; PTHR11081:SF71; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF18380; GEN1_C; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SMART; SM00485; XPGN; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286045}.
FT   DOMAIN          1..95
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00485"
FT   DOMAIN          108..184
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          424..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          761..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        510..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..576
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        585..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        678..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        766..781
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   855 AA;  93687 MW;  8216BF575F54725B CRC64;
     MGIKGIYKEI GPGERISLTK LAVQKLEESG RPLRIAIDIS IWQFQVQAAR GGSNPAIRTL
     FYRLLRLLSL SIQPIFVFDG PNKPAFKRNK RSGRGNGVAT AMAKRLIRLF GFIVHDAPGE
     AEAECALLQQ NAIVDAVLSE DVDTIMFGCT RTLRNWSSEG TKGSKTPTHV SMYDSRGLAQ
     GASGLDREGM VLVALMSGGD YLPEGIPGAG VKLACEAARA GFGKSLCQLK RSNASELASW
     KEWLTYELRH NESGFFRTRH KALTIPDDFP NMEILRYYTH PVVSPAKTLD RLKQQSWDRQ
     IDVQGLREFV RETFDWSYRI GAIKFIRVLA PCLLVRKLMQ YEVEPPSMPG DANVVGTAAS
     GLIQSIKSRR AHFSTDATSE LRISFIPASI VGYDFHEEPD EVIEFGRDGL ALNSDDEIED
     LAEEVEDADP NGKSGTRKPF SPTESDLAWV PEKIARVCIP SMVENWEEAQ RAKAVARSRP
     KASKQKAKSG AMTAGSLDKF VRVKKNSMPQ TAEAKKTTRL PASLGSSPVQ ARTPLDVLPV
     YLQSNPPLPT YSQESQKSRP TRPSKLPTST SSRSERKPPG VPKADTNTNP WTIAGSQGSS
     RVTKSTSFTK APEPILISSS PPPSPPKGVS SSVNHTRDDY NHGELDLSVA LPTSPKKRRP
     AAPSRPTINE ADISSHRIVK GPSTTPISTE KPRCTLARTE SLPGDSSSTS QTRRRLARAQ
     TVAIETLPSD SEDDDDSLEL PPLSSLINKI PKHKNILDLG PSSCLKTPET KPSGQQQNTE
     KKQITLKQSL GVTRMTKLYM PRKSQPGFFK EVEVSVDEAD ILKEELLTAA ATNGGRQAGV
     WRRSDVSCID LTGED
//