ID   A0A443HKP0_BYSSP        Unreviewed;      1315 AA.
AC   A0A443HKP0;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Hydantoinase B/oxoprolinase-domain-containing protein {ECO:0000313|EMBL:RWQ92375.1};
GN   ORFNames=C8Q69DRAFT_488474 {ECO:0000313|EMBL:RWQ92375.1};
OS   Byssochlamys spectabilis (Paecilomyces variotii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX   NCBI_TaxID=264951 {ECO:0000313|EMBL:RWQ92375.1, ECO:0000313|Proteomes:UP000283841};
RN   [1] {ECO:0000313|EMBL:RWQ92375.1, ECO:0000313|Proteomes:UP000283841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 101075 {ECO:0000313|EMBL:RWQ92375.1,
RC   ECO:0000313|Proteomes:UP000283841};
RX   PubMed=30619145; DOI=10.3389/fmicb.2018.03058;
RA   Urquhart A.S., Mondo S.J., Makela M.R., Hane J.K., Wiebenga A., He G.,
RA   Mihaltcheva S., Pangilinan J., Lipzen A., Barry K., de Vries R.P.,
RA   Grigoriev I.V., Idnurm A.;
RT   "Genomic and genetic insights into a cosmopolitan fungus, Paecilomyces
RT   variotii (Eurotiales).";
RL   Front. Microbiol. 9:3058-3058(2018).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWQ92375.1}.
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DR   EMBL; RCNU01000013; RWQ92375.1; -; Genomic_DNA.
DR   STRING; 264951.A0A443HKP0; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000283841; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000283841}.
FT   DOMAIN          13..219
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          238..534
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          668..725
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          741..1274
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1315 AA;  141992 MW;  A2F9567A0C0A6698 CRC64;
     MPHITGADQT KLRIYIDRGG TFCDCIGIVP GKEDIVVKLL SVDPTNYDDA PTEGIRRILE
     IATGEPIPRG CKLDTSNIAS IRMGTTVATN ALLERKGERS ALLITKGFGE LLKIGHQTRP
     KLFDLDIKKP DVLYAKCIEI DERVTIDVPL AEDKDAGTTV HGLSGDVVRI LKPLNEGEVT
     RSLLQLYNED FRSISVCLAH SYTYPQHELR IAEIAKEIGF THISLSSQVA PMIRLVPRGM
     SATADAYLTP TVKRYIDGFT KGFEGGFQQP GKTKCQFMQS DGGLADFRRF SGLRAILSGP
     AGGVVGYAKT SYDPEDGTPV IGIDMGGTST DVSRYAGQLE HVFETTTAGV TIQSPQLDIN
     TVAAGGGSIL FWKNGLFKVG PESAGAHPGP SCYRKGGPLT VTDANLFLGR LLPEFFPKIF
     GPNEDQALDY GIVAEQFQNL TKEINEETGK HLTPEQVAVG FIEVANEGMC RPIRSLTEGR
     GYDARNHRLA VFGGAGGQHA CSIARNLNIN SVVVHKYSSV LSAYGMALAE IVHEGLEPIS
     EVYCAEALSK IRKRLDALQA KVKKELKEEG FDESSLRYER YLNMRYQGTD TSMMIMEPEN
     GDFEQSFLAN HLREFTFTVP GRPILVDDLR VRGVANDGTS IQNVHFVGQL RAAKKHSRDA
     NITDAENTAT VYFEETGWVQ SPVYMLDKLP SGVAVAGPAI ILDKTQTIIV VPGATSIILD
     KHVVIDVGVP TPKEVSADAI DPVQLSVFGH RFMSIAEQMG RTLQKTSVSL NIKERLDFSC
     AIFGPDGGLV ANAPHVPVHL GSMQNAVKYQ HEVNLGKLKP GDVLVTNHPE AGGTHLPDIT
     VVSPVFDEKG KDIIFYTASR GHHRDIGGLG GISGNPNCIF LEQEGARIKS FKLASEGKFD
     EEGITKILVH DPAQYEGCVG SNSINDNLSD LKAQIAANQR GSLLIQELFA AYGTKVVQSY
     MAAIQGTAEL AVRRYLKRVA MTHPDSLKAV DYLDDGTEIH LEVRIDAANG SADFDFTGTG
     PETYGNRNAP SSLVYSAIIY ALRAMINEEI PLNQGCLQPV NIIIPENTVL SPSSGAAVYT
     GNTLTSQRLT DVVFKAFGAC AASQGCMNSV QMYGGEKAEP GEPFAGFTFM YGETLCGGSG
     AGATWRGVSG VHTHMTNTRV SDCEILEKRY PILVKQFSLR HGSGGEGLHP GGDGAIRGFE
     ARAPITFSLS TERRVHRPYG MAGGGPGKSG RNLALLKLPD GRDRWVNVGG KGIIKLRRGE
     QLFIHTPGGG AWGALPNSGI SPGNNYIDGI AKNGEEQHWR GMGSLHNFST AQNEG
//