ID A0A443HY61_BYSSP Unreviewed; 1492 AA.
AC A0A443HY61;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative ABC transporter {ECO:0000313|EMBL:RWQ96671.1};
GN ORFNames=C8Q69DRAFT_201343 {ECO:0000313|EMBL:RWQ96671.1};
OS Byssochlamys spectabilis (Paecilomyces variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=264951 {ECO:0000313|EMBL:RWQ96671.1, ECO:0000313|Proteomes:UP000283841};
RN [1] {ECO:0000313|EMBL:RWQ96671.1, ECO:0000313|Proteomes:UP000283841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101075 {ECO:0000313|EMBL:RWQ96671.1,
RC ECO:0000313|Proteomes:UP000283841};
RX PubMed=30619145; DOI=10.3389/fmicb.2018.03058;
RA Urquhart A.S., Mondo S.J., Makela M.R., Hane J.K., Wiebenga A., He G.,
RA Mihaltcheva S., Pangilinan J., Lipzen A., Barry K., de Vries R.P.,
RA Grigoriev I.V., Idnurm A.;
RT "Genomic and genetic insights into a cosmopolitan fungus, Paecilomyces
RT variotii (Eurotiales).";
RL Front. Microbiol. 9:3058-3058(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWQ96671.1}.
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DR EMBL; RCNU01000003; RWQ96671.1; -; Genomic_DNA.
DR STRING; 264951.A0A443HY61; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000283841; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR005285; Drug-R_PDR/CDR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR NCBIfam; TIGR00956; 3a01205; 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000283841};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 765..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1188..1209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1221..1242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1263..1289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1309..1331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1343..1367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1460..1480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..405
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 848..1091
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 34..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1492 AA; 167056 MW; 1B9A34E85A627124 CRC64;
MSLLGTINPN LNPERGGRAG PWDQENNEDA VRGVANSVST DDTALEEKED KEEQLEQHIS
QLARRLTRES TRYSTKEDLP NPFLDVPEDS TLNPHSPNFK PKNWMKALFA IQSRDPERYP
QRTAGLAFKN LSVHGYGSPT DYQKDVANSV LALGSLVRNI AGSGKQKIQI LRNFDGLIKS
GEMLVVLGRP GSGCSTFLKT IAGEMNGIYM DDSSYMNYQG ISAKQMRGQF RGEAIYTAET
DVHFPQLSVG DTLTFAALAR APRNRLPGVT RRQYAEHMRD VMMAMLGLSH TINTRVGNDF
VRGVSGGERK RVSIAEATLS QSPIQCWDNS TRGLDSANAL EFCKTLRLST EYAGTTACVA
IYQASQSAYD VFDKVAVLYE GRQIYFGRTE EAKEFFTTMG YECPERQTTA DFLTSLTSPA
ERIVKPGYEN LVPRTPDEFA AAWKKSDAYA KLMKEIDEYE RTYPIGGESY QKFVEARRAQ
QAKSQRIKSP YTISVYEQVK LCVWRGFLRL KGDASLTLTQ LIGNTIMALI IGSVFYNLRK
DTGSFYARGA LLFFAVLLNA FSSALEILTL YAQRPIVEKH ARYALYHPFT EAIASMLCDV
PYKLLNATTF NLTLYFLTDL RREPGAFFIF YLFSIVTTFA MSMIFRTIAA SSRTLAQALA
PAAILILGLV IYTGFTIPTR NMLGWSRWMN YLDPISYAFE SFMVNEFHDR TFECAANQIV
PTGPGYENVP MANKICSTVG AVAGQSTVQG NLYLSKSFEY AKSHLWRNLG IMFGFMVFFM
FTYLVASEYI TEAKSKGEVL LFRRGHQPVA ARKASDDVET QPEPVPAEKT EVNNGHTTAA
IQRQTAIFQW QDVCYDIKIK GEPRRILDHV DGWVKPGTAT ALMGVSGAGK TTLLDVLATR
VTMGVVTGEM LVDGRPRDQS FQRKTGYVQQ QDLHLSTSTV REALRFSAIL RQPAHVSRQE
KLDYVEEVIK LLGMESYADA VVGVPGEGLN VEQRKRLTIG VELAAKPQLL LFLDEPTSGL
DSQTSWSILD LIDTLTAHGQ AILCTIHQPS AMLFQRFDRL LFLARGGKTV YFGEIGEKSS
TLSSYFERNG APKLPPDANP AEWMLDVIGA APGSHTDIDW PAVWRESPER KAVHEHLAEL
KSTLSQKPVD SSVTDPSSYK EFAAPFSVQL YECLVRVFAQ YWRTPSYIYS KSALSILTAL
YIGFSFFHAQ NSLQGLQNQM FSIFMLMTIF GNLVQQIMPN FCTQRSLYEV RERPSKTYSW
QSFMTANILV ELPWNTLMAV FIFVCWYYPI GLYRNAEPTD AVHERGALMF LLIWTFLLFT
STFAHMIIAG VELAETGGNL ANLLFSLCLI FCGVLATPEA LPGFWIFMYR VSPFTYLVSA
MLSTGVSGTN VVCEDVELLR FDPPSNMTCG DYMNPYISKA GGYVANPDAT TNCGFCQMSD
TDTFLATVSS YYKDAWRNFG FMWIYIFFNV VAAVGIYWLA RVPKGKRTKG TT
//
