ID A0A443PR79_9MAGN Unreviewed; 441 AA.
AC A0A443PR79;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00013189};
DE EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189};
GN ORFNames=CKAN_02253100 {ECO:0000313|EMBL:RWR93288.1};
OS Cinnamomum micranthum f. kanehirae.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Magnoliidae; Laurales; Lauraceae; Cinnamomum.
OX NCBI_TaxID=337451 {ECO:0000313|EMBL:RWR93288.1, ECO:0000313|Proteomes:UP000283530};
RN [1] {ECO:0000313|EMBL:RWR93288.1, ECO:0000313|Proteomes:UP000283530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chaw 1501 {ECO:0000313|Proteomes:UP000283530};
RC TISSUE=Young leaves {ECO:0000313|EMBL:RWR93288.1};
RX PubMed=30626928; DOI=10.1038/s41477-018-0337-0;
RA Chaw S.M., Liu Y.C., Wu Y.W., Wang H.Y., Lin C.I., Wu C.S., Ke H.M.,
RA Chang L.Y., Hsu C.Y., Yang H.T., Sudianto E., Hsu M.H., Wu K.P., Wang L.N.,
RA Leebens-Mack J.H., Tsai I.J.;
RT "Stout camphor tree genome fills gaps in understanding of flowering plant
RT genome evolution.";
RL Nat. Plants 5:63-73(2019).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWR93288.1}.
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DR EMBL; QPKB01000010; RWR93288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443PR79; -.
DR STRING; 337451.A0A443PR79; -.
DR Proteomes; UP000283530; Unassembled WGS sequence.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR CDD; cd05247; UDP_G4E_1_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005886; UDP_G4E.
DR NCBIfam; TIGR01179; galE; 1.
DR PANTHER; PTHR43725; UDP-GLUCOSE 4-EPIMERASE; 1.
DR PANTHER; PTHR43725:SF51; UDP-GLUCOSE 4-EPIMERASE; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000283530}.
FT DOMAIN 97..422
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
SQ SEQUENCE 441 AA; 48786 MW; 0615C0B094E8A5A0 CRC64;
MSILPFLRFP HPRRPATHLQ VGSCVWKSKP PFNNTYYYYK YSLPSFPISS QHLSDLKFLI
HFHFSSVCNS LISFFFFFSS GSISSTFSTA AMAKSILVTG GAGYIGSHTV LQLLLGGFKV
VVVDNLDNAS EIAVKRVAEI AGEVGKKNLV FHKVDLRDKE ALGKIFAASS FDAVIHFAGL
KAVGESVQKP LLYYNNNIIG TINLLEVMAA YGCKKLVFSS SATVYGWPKE VPCTEDFPLC
ATNPYGRTKL FIEEICRDIF RGDSDWKIIL LRYFNPVGAH SSGYIGEDPR GIPNNLMPFV
QQVAVGRRPA LTVYGNDYST QDGTGVRDYI HVVDLSDGHI AALRKLFDGS NIGCEVYNLG
TGKGTSVLEM VAAFEKASGK KIPLVMAGRR PGDAEIVYAS TDKAERELKW KAKYGVEEMC
RDQWNWASKN PYGYESPDCT N
//
