ID A0A443Q8C5_9ACAR Unreviewed; 575 AA.
AC A0A443Q8C5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=NAD(+) ADP-ribosyltransferase {ECO:0000256|ARBA:ARBA00012020};
DE EC=2.4.2.30 {ECO:0000256|ARBA:ARBA00012020};
DE Flags: Fragment;
GN ORFNames=B4U79_09772 {ECO:0000313|EMBL:RWR99228.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWR99228.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWR99228.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWR99228.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the ARTD/PARP family.
CC {ECO:0000256|ARBA:ARBA00024347}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWR99228.1}.
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DR EMBL; NCKU01016289; RWR99228.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443Q8C5; -.
DR STRING; 1965070.A0A443Q8C5; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd17747; BRCT_PARP1; 1.
DR CDD; cd08001; WGR_PARP1_like; 1.
DR Gene3D; 3.90.640.80; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 1.20.142.10; Poly(ADP-ribose) polymerase, regulatory domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR049296; PARP1-like_PADR1_N.
DR InterPro; IPR012982; PARP1-like_PADR1_Zn_ribbon.
DR InterPro; IPR004102; Poly(ADP-ribose)pol_reg_dom.
DR InterPro; IPR036616; Poly(ADP-ribose)pol_reg_dom_sf.
DR InterPro; IPR036930; WGR_dom_sf.
DR InterPro; IPR008893; WGR_domain.
DR PANTHER; PTHR10459; DNA LIGASE; 1.
DR PANTHER; PTHR10459:SF112; POLY [ADP-RIBOSE] POLYMERASE 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF21728; PADR1_N; 1.
DR Pfam; PF08063; PADR1_Zn_ribbon; 1.
DR Pfam; PF02877; PARP_reg; 1.
DR Pfam; PF05406; WGR; 1.
DR SMART; SM01335; PADR1; 1.
DR SMART; SM00773; WGR; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF47587; Domain of poly(ADP-ribose) polymerase; 1.
DR SUPFAM; SSF142921; WGR domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS52007; PADR1; 1.
DR PROSITE; PS51060; PARP_ALPHA_HD; 1.
DR PROSITE; PS51977; WGR; 1.
PE 3: Inferred from homology;
KW ADP-ribosylation {ECO:0000256|ARBA:ARBA00022765};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 137..210
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 305..405
FT /note="WGR"
FT /evidence="ECO:0000259|PROSITE:PS51977"
FT DOMAIN 426..544
FT /note="PARP alpha-helical"
FT /evidence="ECO:0000259|PROSITE:PS51060"
FT NON_TER 575
FT /evidence="ECO:0000313|EMBL:RWR99228.1"
SQ SEQUENCE 575 AA; 65096 MW; 7B392C45E234FBDF CRC64;
MKRTDIVRLL EYNNQHVPES NSSKYERLAD CMVFGALEKC PECKNGQLVF RIAGYICTGH
ISEWTTCLYQ TQTPARKSFK IPEDIRDSYD FLSTYEFKEH KRVYNKVEAP TSAVNHIERA
MQPSTSSTSA IENGTDVAKL PLKGHKVAYV GKMKLSKRAL KEKILSLGGK LVDEIDRTVL
FIISTQKEVE KEGAKIAKAK TCGVTVVSED VFDALNEKVD ICDLIKRNTI SPWGGDVSKK
HKTLVDKDKL KSGSGEPILC TDTGLTFSFL GMKSGSGSSK SEPKIQSFKM KAGLVVDPDS
GLDHVAHVYK DHNGPYSVVL AKVDIVSNKN SYYKIQLLES DEAKKKHQYW VYRAWGRIGT
DIGGDKLEKF KLKSNAIDNF CEVFLEHTGN EWKKKKEFKK LPGRYHIVET HYGNSLDDDK
KLVVGNSCLP LPVQDLITMI FDISRMKHQM QEFHLDLAKM PLGKISKDQV MSAYAVLNEI
SCMIETNEKS LTKMLDASNR FYSLIPHDFG TDNVIVIKNK ELLQEKLEML DSLLEMELAF
ELVSDIKEEG EDVLKQHYDR LDANIEVLDK NSEEF
//
