ID A0A443R1P3_9ACAR Unreviewed; 558 AA.
AC A0A443R1P3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Axin-1-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B4U79_14654 {ECO:0000313|EMBL:RWS09186.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS09186.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS09186.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS09186.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS09186.1}.
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DR EMBL; NCKU01002620; RWS09186.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443R1P3; -.
DR STRING; 1965070.A0A443R1P3; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR043581; Axin-like.
DR InterPro; IPR014936; Axin_b-cat-bd.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46102; AXIN; 1.
DR PANTHER; PTHR46102:SF2; AXIN; 1.
DR Pfam; PF08833; Axin_b-cat_bind; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 36..169
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 471..555
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT REGION 297..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 558 AA; 65044 MW; CC72311CA84E4512 CRC64;
MSVIRSEQGA KANCPNRRER WLHSNDCKTP SKWSQDFRSL IDDYDGYKLF EQYLEEIQFA
PLLKFWCVLR GFKREYKNKD VRDMFRAANV IYKQLFKPKS GENKLIHDWV KEETKNNIAT
CLRSFSEESC KDKSRIINVF VEAQRELEER MRKNFYDDFL RSEIFLNYVQ KLEIQCKPEE
ANSQSSNAEI FINELPKDAF KPLEGEKSSR FIPKTEYSNI QEKTMEGTLP SVPKIGDRML
KFLNEKLCQI KKEKEKKEKD EKEANYTLSK MRKLNGERFS GLPPQLLLDA MKDKLTNTSG
NDASDQSILD EHISRVFSPD NSPITRSRSE VKPLPSNSLS SNPPLSRDDY IIDGLHSNVL
PNDKYIYYPK KAQMNKHEAY KWSVTQNCND SEQINQENKA FYRNRHKPLS MQRAFGDGIS
TTNLNVISEE SSFTQRRQEF DCMLKSLPTP MYPSVVNDKF QSKVDATLKA TDILTVGYRF
AEDEVPYVKK LQGCHSLTLA QFKQLIPPRK GPSSFYFRKE SNEFGTGYVM EEIFDDNEFL
PIIEGKKIYC VIDSGLRH
//
