ID A0A443RCG2_9ACAR Unreviewed; 1024 AA.
AC A0A443RCG2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Superkiller viralicidic activity 2-like 2 {ECO:0000313|EMBL:RWS12962.1};
GN ORFNames=B4U79_01151 {ECO:0000313|EMBL:RWS12962.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS12962.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS12962.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS12962.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS12962.1}.
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DR EMBL; NCKU01001147; RWS12962.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443RCG2; -.
DR STRING; 1965070.A0A443RCG2; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301}.
FT DOMAIN 132..288
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 391..563
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 39..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 584..611
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 39..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1024 AA; 116834 MW; DD2CD74C24A6E0FA CRC64;
MDLELFDVFE SGEDKLTTEQ CGKRKKCDEN DDIDLMEIIE KESANPENVA KKTKSDEKND
DFDEKEDEKE KLEEMLPRVS INSLETKEGC LHEVVTPVDI EYAPLRDLSG TENHKPAKEY
DFSLDPFQKE AIICIENNQS VLVSAHTSAG KTVVAEYAIA QSLRDKQRVI YTTPIKALSN
QKYREFYEEF QDVGLITGDV TINPTASCLI MTTEILRLML FRGSEVMREV GWVIFDEIHY
MRDRERGVVW EETIILLPDS VHYVFLSATI PNARQFAEWI SHLHHQVCHV VYTDFRPTPL
QHYVFPAGGD GLHLVVDESG NFREDNFNVA MSVLQNAGDA AKGDAANKGR KGGIKGDSDC
FKVIRTIMER NLAPVIVFSF SKKECEAYAL KMSKLDFNTN EEKNLVTEVF NNAIDILSEE
DKKLPQVEHV LPLLKRGIGI HHSGLLPIIK ETIEILFGEG LIKALFATET FAMGLNMPAR
TVVFTNAHKF DGTDFRWITS GEYIQMSGRA GRRGIDERGI VILMVDEKMS PSVGKELIKG
KPDPINSAFH LTYNMVLNLL RVEDVNPEYM LQHSFYQFQH YAEVPELLEK LKALEAQYEK
IEVENEAKVG DYFKIKSELS HLSKQFLEYL RKPTYIVPFL QNGRLLKIVS DEGVEVGWGV
LVNFLKKPSK KRNPAIDEAF VYTLDVIINI DSAYERRNGE IRPPLAGEKG DMKIVTFSLN
NITQISSVRV FCPHDLKSHD SRESVRKTLN KVYKEFSNKV PLLDPIEDMK IKDKEFLSLV
TKIEAYERRL LQCEDIDPIA MEAYSRKQAI GEKIRKVKAD LKKAQSLLQM DELKCRKRVL
RRLGYCTAAD VIEIKGRVAC EITSGDELMI TEMLFNGLFN DLNIYQINAL LSCFVFEEKA
EKTEKLTEEL AQPLRQMQQL AKRIATVSKE AKLDIDENAY VESFRPNLMD VVYAWSKGAS
FAQLCKMTDA FEGSIIRCLR RLEELLRQMC QAAKVIGNTD LENKFSEANK AIKRDIVFAA
SLYL
//
