ID A0A443RY53_9ACAR Unreviewed; 426 AA.
AC A0A443RY53;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
DE Flags: Fragment;
GN ORFNames=B4U80_02926 {ECO:0000313|EMBL:RWS20154.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS20154.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS20154.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS20154.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}.
CC -!- SIMILARITY: Belongs to the anoctamin family.
CC {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU280814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS20154.1}.
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DR EMBL; NCKV01019652; RWS20154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443RY53; -.
DR STRING; 299467.A0A443RY53; -.
DR EnsemblMetazoa; LDEU011886-RA; LDEU011886-PA; LDEU011886.
DR VEuPathDB; VectorBase:LDEU011886; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF83; ANOCTAMIN; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW Reference proteome {ECO:0000313|Proteomes:UP000288716};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU280814};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU280814}.
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 93..111
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 219..246
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 267..290
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 366..387
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT DOMAIN 5..401
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RWS20154.1"
SQ SEQUENCE 426 AA; 48503 MW; CCC25B0AB0FDEC04 CRC64;
LSGVSVLLLV LVAFSALIGV IVYRVSVSAA LAANADRGVA RYSSMITSAT AAFLNLICIM
ILNQFYTRLA FRLTELEMPR TQSDFDNSLT LKMYLLQFVN FYSSIFYIAF FKGRFVGYPG
DLTDDTSAFS KRTQEACGTG GCFVELTIQL AIIMIGKQAL NAFMEMVNPW VQSLLHRWSL
GDTTETDFQN APQWEADYVL ALWKPQALFY EYLEMVLQFG FVTIFVAAFP LAPLFAIINN
VFEIRLDAKK MISQMRRPVA KRVKDIGVWY GILEVIGKLA VLSNALIIAF TSDFIPRIYH
LAKYGSMETY VNETLSFYES KEFNKFNITP VSSKWCMYLG NRYPPNAGEN KYKPTTDYWE
ELAVKFAFVV IFENIIAAFT MILAWAIPDI PASLKRQIKQ HEYMTNELIM HTEVERSKVT
QNDKSD
//
