ID A0A443S5L1_9ACAR Unreviewed; 411 AA.
AC A0A443S5L1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=COP9 signalosome complex subunit 3 {ECO:0000256|ARBA:ARBA00014878};
GN ORFNames=B4U80_00136 {ECO:0000313|EMBL:RWS22858.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS22858.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS22858.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS22858.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN3 family.
CC {ECO:0000256|ARBA:ARBA00007084}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS22858.1}.
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DR EMBL; NCKV01007725; RWS22858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443S5L1; -.
DR STRING; 299467.A0A443S5L1; -.
DR EnsemblMetazoa; LDEU009182-RA; LDEU009182-PA; LDEU009182.
DR VEuPathDB; VectorBase:LDEU009182; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR10758:SF1; COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000288716};
KW Signalosome {ECO:0000256|ARBA:ARBA00022790}.
FT DOMAIN 195..363
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 411 AA; 47096 MW; F7C2441EABDF4852 CRC64;
MALEQFVVNI RNFSSSGQFE HLYEFCTKNS DVLVKQSAHL DDALATLDLQ EHSLGILAIL
CVKMSLSQNQ EVEQLYAQIQ EFITECNGEQ IRFATDTFAE LCHCYTLSLV ERRQPMRGIY
LLCKAISKIQ LSPTQLTSIH ADLIQLCLLA KCLKPALQFL DLDITDISKE GGQFDVKYFL
LYYYYGGMVY AALKNFERAL YFFEVAITTP SMAVSHIMLE AYKKYVLIAL ILYGKVPPLP
KYTSQVVTRF IKPLSAPYNE LVSAYATNNP EEVMAVISRH SDTLTRETNM GLVKQCLSSL
HKKNIQRLTK TFLTLSLSDM ASRVQLANAK EAEEYILRMI EDKEIFASIN QKDGMVVFLD
NPEKYNTSTM FRRLEDDMKI CMYLDEKLRK MDQEIAVSSK YIQKIRVESD S
//
