ID A0A443S7D2_9ACAR Unreviewed; 485 AA.
AC A0A443S7D2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=E3 ubiquitin-protein ligase MIB2-like protein {ECO:0000313|EMBL:RWS23456.1};
GN ORFNames=B4U80_09381 {ECO:0000313|EMBL:RWS23456.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS23456.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS23456.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS23456.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Target cell membrane {ECO:0000256|ARBA:ARBA00004175}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS23456.1}.
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DR EMBL; NCKV01006416; RWS23456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443S7D2; -.
DR STRING; 299467.A0A443S7D2; -.
DR EnsemblMetazoa; LDEU008584-RA; LDEU008584-PA; LDEU008584.
DR VEuPathDB; VectorBase:LDEU008584; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0044231; C:host cell presynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0044218; C:other organism cell membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13857; Ank_5; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Membrane {ECO:0000256|ARBA:ARBA00023298};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Neurotoxin {ECO:0000256|ARBA:ARBA00022699};
KW Presynaptic neurotoxin {ECO:0000256|ARBA:ARBA00023028};
KW Reference proteome {ECO:0000313|Proteomes:UP000288716};
KW Target cell membrane {ECO:0000256|ARBA:ARBA00022537};
KW Target membrane {ECO:0000256|ARBA:ARBA00023298};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REPEAT 36..68
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 69..101
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 214..246
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT COILED 406..433
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 485 AA; 54032 MW; 61240D5E20CE4CF2 CRC64;
MENKTKRLQN CASSGNIVEV KRLIEQKVDV NARDGYGNTV IHHAIKGNQV PILQLLFISG
VDINAVNDDG CTALHLAVKS GREKCVTALL NRNAQVNLVN KDGLTELMVA MKIDDHIDKG
HRNRTIEHLL NFPRINVREL SYDRQKHTAL HIASQCGNLF AVNRLLEKDP ALYNIRNAFG
NLAIHNAAAY GYPKIIEELR RIFPKLDLNV KGFNSRTPLQ MAVMSHQFLT IELLIELNAD
CNIGDEEGNT ALHTAVNIFN CCCSKGLSDT NNCQKEVDHG LKIKKIKHSL SATVHNKCYS
LALVAFLIDE GNGNIYVENN AGDTPLDLVA HEKLISNLLK SIHYQKLERH ASQENHDFEA
VESSDIQAVS LEDLEKQLND FTPDDVIITE VEVTPPSCST ACGQKIMILE SKIENLERTI
KKMSDEFEAM KMCFASNNQQ EYNQCGLCTK SATYSLLCGH KLCDDCYDTN SSNCITCNGN
VTECS
//
