ID A0A443SL30_9ACAR Unreviewed; 844 AA.
AC A0A443SL30;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=CCR4-NOT transcription complex subunit 3-like protein {ECO:0000313|EMBL:RWS28209.1};
GN ORFNames=B4U80_02308 {ECO:0000313|EMBL:RWS28209.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS28209.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS28209.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS28209.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS28209.1}.
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DR EMBL; NCKV01001516; RWS28209.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443SL30; -.
DR STRING; 299467.A0A443SL30; -.
DR EnsemblMetazoa; LDEU003830-RA; LDEU003830-PA; LDEU003830.
DR VEuPathDB; VectorBase:LDEU003830; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:2000036; P:regulation of stem cell population maintenance; IEA:UniProt.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04153; NOT2_3_5_C; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000288716};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..232
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT DOMAIN 726..838
FT /note="NOT2/NOT3/NOT5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04153"
FT REGION 245..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 522..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 41..68
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 844 AA; 93260 MW; CDA5657D52B5FD2D CRC64;
MADRRKLQGE IERCHKKVQE GVETFEDIWQ KAHNAPNSNQ KEKYETDLKK EIKKLQRLRD
QIKTWLASSE IKDKRLLLED RKLIETQMER FKVLERETKT KAYSKEGLGA AQKLDPAQKE
KDEVTNWLSY SIDNLNMQVD QFECEIETLS VGLKKKKSDK EKQDKLDKLK AWVEKHRFHI
NQLETIMRML DNSTVDVDQV KKIKDDVEYY IESSQEPDFE ENEFLYDDLE LEDMQEYLLK
RATSAGNHTS SSFDSGTTKN SSNTTGDEEG SNSVQSNTPT SNSSSPAPSP GLTNHSKGAL
YENNLSIAIS SCTTVNNSNS ISSSSSGAST LVKPMPVWSH NTSVSSSISC VSSSVSSSKV
MNASQPSTLT TTSTTTTPSR NNSSTSSNSS SPSVNSVNNH NTNSASSTLY AVAASTAVLN
NCNNRITHSL GDNCVKSDSV ISDGLLSNSS TPPTLNAGLP HSTSPPNILP LSPLISLQDS
AQQQQQLLLQ NNSQLQQLQL TSPAATTSSA LYSVAAASSS TSSTVSSDPW NNTVATSRSQ
NVSHSQTNSL LINGPLIHDG LKLQNQLQQH QSTPMSSLKS MAQQAVVSAG LEVQINSQNE
IQQQTPQVAT IFDSGVLSTS NAHTINSIVT SSAPSVIGLL SATSKSIGPI APPVIPASVV
NLSIRTPGVT SPATTGVQQS EANIPPLLGV APLGPIQLPK SCIYQLHMLE AASRHTVHPI
DSQRLRPYLS PNVCPVPSYY PQQALPHCDT VDFFHRLSTE TLFFVFYFME GTKAQYLAAK
ALKKQSWRFH TKYMMWFQRH EEPKTITDEY EQGTYIYFDY EKWGQRKKEH FTFEYRYLED
RDLN
//
