ID A0A443SPT5_9ACAR Unreviewed; 651 AA.
AC A0A443SPT5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Voltage-dependent L-type calcium channel subunit beta-2-like isoform X1 {ECO:0000313|EMBL:RWS29524.1};
GN ORFNames=B4U80_02091 {ECO:0000313|EMBL:RWS29524.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS29524.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS29524.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS29524.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS29524.1}.
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DR EMBL; NCKV01000874; RWS29524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A443SPT5; -.
DR STRING; 299467.A0A443SPT5; -.
DR EnsemblMetazoa; LDEU002515-RA; LDEU002515-PA; LDEU002515.
DR VEuPathDB; VectorBase:LDEU002515; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd11863; SH3_CACNB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824:SF5; CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L; 1.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000288716};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 61..130
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 153..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 72625 MW; 47E7B3DF91D93077 CRC64;
MPSVTVRCCL SPFVLQLHRG SADSNYSQPS SDLSLDEERE TLRRETERQA LAQLEKAKTK
PVAFAVRTNI AYDGSVDDDS PVHGYAVSFG VKDFLHIKEK YNNDWWIGRL VKEGSEVGFI
PSPVKLENLR LQQTQASRTK LYASKTGSGS NLGGLVNNVL NNSQSNSRGS TPPTPDQNGE
NICDESDNTS RLPKNAVSTP PAKEKRKPFF KKSENIPPYD VVPSMRPVVL VGPSLKGYEV
TDMMQKALFD FLKHRFEGRI IITRVTADIS LAKRSLLNNP NKRALMDRSN ARSSCLAEVQ
AEIERIFELA RTMQLVVLDC DTINHPSQLA KTSLAPITVY VKISSPKVLQ RLIKSRGKSQ
SRNLNVQMVA AEKLAQCPPE MFDVILDENQ LEEACEHMCE FLEAYWRATH PPVKATPTGH
HLPSSSRPPL PPTSPHHTTA KMMYETEMNS PLGDRMEPTD MSRYRSRNAT TSLDVPSSRP
VVSDGFSPES GSPTEFYEPH LRQDIRTARD YSAMARSRQM QSAYGPGTDP MDEPYYYAGT
STSVPGASRY NDLPPSDSPT VVDRDFSDRA EWMSSAVASS SHMSPARTYQ HSSDRYPEDY
ELYADPHSVH LRDNDPYYDA YVDYQFVANP TGQGLQSSAS RSVPGRPKNA L
//
