ID A0A443SRP7_9ACAR Unreviewed; 1330 AA.
AC A0A443SRP7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Calmodulin-regulated spectrin-associated protein 2-like protein {ECO:0000313|EMBL:RWS30210.1};
GN ORFNames=B4U80_10462 {ECO:0000313|EMBL:RWS30210.1};
OS Leptotrombidium deliense.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombiculoidea; Trombiculidae; Leptotrombidium.
OX NCBI_TaxID=299467 {ECO:0000313|EMBL:RWS30210.1, ECO:0000313|Proteomes:UP000288716};
RN [1] {ECO:0000313|EMBL:RWS30210.1, ECO:0000313|Proteomes:UP000288716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-UT {ECO:0000313|EMBL:RWS30210.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS30210.1}.
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DR EMBL; NCKV01000593; RWS30210.1; -; Genomic_DNA.
DR STRING; 299467.A0A443SRP7; -.
DR EnsemblMetazoa; LDEU001830-RA; LDEU001830-PA; LDEU001830.
DR VEuPathDB; VectorBase:LDEU001830; -.
DR Proteomes; UP000288716; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF0; PATRONIN; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}; Reference proteome {ECO:0000313|Proteomes:UP000288716}.
FT DOMAIN 148..279
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1196..1329
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 291..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1053..1101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1138..1164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1014..1044
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 291..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..786
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..987
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1058..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1138..1158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1330 AA; 150978 MW; 63D7D85E509E33A3 CRC64;
MQAKQKSSIL WILSKAYNNE IPPDLLDPYY KDNEEQDKLK PQIVQSLANT EIYCLSLSNI
YADPNYSCLN HHEIMQLLMR KGIYVVEPND TSLTETVLLQ TAPIRLSAHM VIIEAIMALY
IKEVLIPEKL VEVVSRFIAI DPEEPLPSDP EEAAIFWMNK SCIRMKQRMD DELFHLGNDN
VVSPPLLVLE DLADLSDGCS LATLLSFYCP EQLNWTEICF NESMGMADSI YNLQLVQYFC
QEKLPHNICF LSLEDFLYLH ETIRPNVLAF IADLLFLFEI KPSPFVRRPG TKEELGFSDS
EEETFKGLPD LPTPAEMKSK SLQHSGWANS DYRNSREDSK SQRSFQRSLR RLERSDEEDT
FQHCSMESGV PSDRYPDVIF SKPYDTVSVS NFSKPLTKYK FQELQRSHSA SKSRSPTRSE
KSDTVSDISS VEKEKHSPTL TTNFMKISRS KDVNGSQSEN HSENQTTPVI NIAFKQKDAN
EYSMNSIRAS QKPFQLNDGS SIKDIFNQKP NQTNIVEQEK SSDDVQTLLR DIRLKLEAKR
HKLEAENKNV NQAWKQQALL KAVKTQKDDK EVEVKDDEKC NGGGDNVDVE ELKHDLEEMS
KRLAEHEKLS TLRRVSNSDK QTPDKKIDPE SASEAHQQKP NYNAQHERFE LNSSEIPSSL
PNQIRFDNSS QHLGNSPHAA AFNEPQMIPK RSKWGQPSVP FAANDLEYQW TVASIPPQVE
HPFYPRYPAN PYEHMYSMHM YPTHAPLQPR SVYGYQHPET YYRPHLPPQT SNHGHPIYSQ
PNEMYRTPDN RDFVPFSPPT HHLNYSQNVG SNVNPPTVVE HNEDSLKSRN RLLNQSVNNE
SRKLKDSRSN HDLRKDLSNT FQERSPTLTQ TITRSSHRTS SSCEPSQGIN RKKSVDSEAS
SSDSIHNKNG SSSDSLSNKD DDLTFTQKGF FIHFGDDDSK PKPKPAVRPK LRSQQKPQLA
IESDFTRQHE NHRESVKSSK EKKPSNEVKL SPVSQGVGFV IGQDLVDPDP CLELEMAKKK
EKKKEEASKK KEEERLRRQI ILEQYRQRKI QEEADKNGLS GAVSSVSSKD SSRNNTVVLH
RPARGRPNSS GTKPRPKSYH VSASQMQDFV SLDPKASRIT DDVDAVYNFG SSMSSVVGSS
CSRPQSALSG TTTMPRRLPS PPSRLPAIPS NLLGRHRGPP SDGASDAGST FSEYTGPKLF
VKPTQKSNRG LIINASNVVL AGAVNAETKK RVLEEINVSD SKHFVILFRG AGMQFRAIYS
YNPDREEVFK LYGTGPKTIN NDMIDKFYKY NSGTKSFNEV QTKHLTVTID AFTIHNTLWS
GKRMSTKNIF
//
