ID   A0A444H8I2_9FLAO        Unreviewed;       420 AA.
AC   A0A444H8I2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Putative DNA modification/repair radical SAM protein {ECO:0000313|EMBL:RWW99584.1};
GN   ORFNames=EPI11_11565 {ECO:0000313|EMBL:RWW99584.1};
OS   Flavobacterium cerinum.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=2502784 {ECO:0000313|EMBL:RWW99584.1, ECO:0000313|Proteomes:UP000287527};
RN   [1] {ECO:0000313|EMBL:RWW99584.1, ECO:0000313|Proteomes:UP000287527}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1E403 {ECO:0000313|EMBL:RWW99584.1,
RC   ECO:0000313|Proteomes:UP000287527};
RA   Zhang R., Du Z.-J.;
RT   "Flavobacterium sp. nov.,isolated from freshwater.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWW99584.1}.
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DR   EMBL; SBII01000008; RWW99584.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A444H8I2; -.
DR   OrthoDB; 9801154at2; -.
DR   Proteomes; UP000287527; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR023874; DNA_rSAM_put.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR010994; RuvA_2-like.
DR   NCBIfam; TIGR03916; rSAM_link_UDG; 1.
DR   PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR21180:SF9; RADICAL SAM DOMAIN PROTEIN; 1.
DR   Pfam; PF12836; HHH_3; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01102; Uncharacterised_Radical_SAM_Su; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287527};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          61..188
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|Pfam:PF04055"
SQ   SEQUENCE   420 AA;  47731 MW;  A972D31DB76FA1D6 CRC64;
     MYDRIREKLS ILADAAKYDV SCSSSGGNRK NDNKGIGDSS ASGICHTYTE DGRCVSLLKI
     LLTNHCVYDC AFCVSRKSND VKRAAFTVDE VVELTMSFYR RNYIEGLFLS SGIFKNADFT
     MERLVRIAKR LRLEERFNGY IHLKTIPGAS QELLTEAGLY ADRMSINLEM PTEMGLKLLA
     PEKSHDDVKM PLGFIKDTIA KFKDEKKTGL IKSIPKFVPA GQSTQMVIGA TPETDMEIMY
     SADEYYKNFS LKRVYYSGYI PISHDSRMPV IGSQPPLLRE NRLYQTDWLM RFYGFNVKEL
     LNTNNPHLDT DIDPKLSWAL RNLEQFPVDI NTADYHMILR VPGIGVNSAQ KIVQARKFGK
     LRSDQLKKIG ISYNRAKHFI RCADSPIILN EPDAPHLKSI ILTESSSKYL KVPQNQLSLF
//