ID A0A444HBI6_9FLAO Unreviewed; 630 AA.
AC A0A444HBI6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RecQ family ATP-dependent DNA helicase {ECO:0000313|EMBL:RWX00832.1};
GN ORFNames=EPI11_07370 {ECO:0000313|EMBL:RWX00832.1};
OS Flavobacterium cerinum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2502784 {ECO:0000313|EMBL:RWX00832.1, ECO:0000313|Proteomes:UP000287527};
RN [1] {ECO:0000313|EMBL:RWX00832.1, ECO:0000313|Proteomes:UP000287527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1E403 {ECO:0000313|EMBL:RWX00832.1,
RC ECO:0000313|Proteomes:UP000287527};
RA Zhang R., Du Z.-J.;
RT "Flavobacterium sp. nov.,isolated from freshwater.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWX00832.1}.
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DR EMBL; SBII01000004; RWX00832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A444HBI6; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000287527; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:RWX00832.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000287527}.
FT DOMAIN 25..193
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 217..363
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 630 AA; 72267 MW; 959AF74429839C7E CRC64;
MQQALDILKK YWHHDTFREP QDKIIQTVLE GKDTFTLMPT GGGKSVCFQI PSMMKDGICL
VISPLVALMK DQVANLAKRD IKAIALTGGI STSELSDLLD NCRFGNYKFL YLSPERLQSD
WIIERIKELP INLVAVDEAH CVSQWGHDFR PAYLKISALK KHLPHVPFLA LTASATQRVQ
EDIITQLGLK DPVVFKKSFA RENIAYMVFE TEDKLRRIQQ ILTKNPEPSI IYVRNRKSCH
DIAHQLQSLG YTATFYHGGL KEKEKEANMQ AWLKEKAQVI VATNAFGMGI DKPNVRTVIH
IQLPENLENY YQEAGRSGRD GKKSFAVLLV SPSDVDIAKS QFIEVLPDKK FLKEVYLRLN
SYLQIAYGEG IDETFPFNFN EFCQRYKLPV IKTYNALQFL DRQGIMTLSQ EFTEKIALQF
IIPSKEVMRY ISLNPADEET ILVILRNYSG IFDMETSLNT SLVTKKAKIT EQELLNLLQR
LQHKGVITYR SSGNDSSITF NEVREDNHTI NRISKFLENQ NEIKTRQFES VVNYTSNTTR
CKSRLILDYF DEKENSDCGI CSYCITKNKT IKSPLEIANA ILDLLKISSL DSKELEQKLE
LTAQEIVFSL QLLLEHNKIR INTNNKYTLK
//
