ID A0A444XDJ6_ARAHY Unreviewed; 1612 AA.
AC A0A444XDJ6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=Ahy_B09g095291 {ECO:0000313|EMBL:RYQ87752.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYQ87752.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYQ87752.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYQ87752.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYQ87752.1}.
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DR EMBL; SDMP01000019; RYQ87752.1; -; Genomic_DNA.
DR STRING; 3818.A0A444XDJ6; -.
DR Proteomes; UP000289738; Chromosome b09.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000289738}.
FT DOMAIN 8..177
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1088..1188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1515..1536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1576..1612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1088..1183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1612 AA; 184368 MW; F43D95F794D4C0C4 CRC64;
MSSSSCTTKY DVFISFRGED TRETFTVHLF NALANKTIRA YMDCLLQRGD EVWPALEKAI
EGSLISIVVF SENYATSKWC LEELVKILQW REYHGQVVIP VFYRTDPSDI RNQSGSFEKA
FAKYERDLAE SESNRDKISK WREALKKSAN ISGWHSRNYA DDHELIRKVV NDVLKMRILK
HPIVPTGLVG IEEIRKIVKV NMKQHRVIGI WGMRGIGKTT IAKMLFAKSF PHYDHVCYAE
NAKEYTPQRL LSELLRERIT TDATGFVNSM SSLSNKKVLI ILDNVKDSDQ PLLEAVCQGY
KSHSRESKLI ITTTHKHLLE KRVDWTFEVK QWDDSKSIEL LSLKAFEESI PPKPYEILVN
KVVKYAGGIP LALNLLGSYL QSRSIEFWES TLEKLQKHPI KRIQAAFTES YDELDDLDKE
IFLDIAFFFH GEKKDLVTSI LKACEFSPIR GIEILQDKAM ITTIPYKETI EMHGLLREMA
YEIVHEENSK DPRKRSRLKD TEDICVVLKE NKKSLDAIEG IILDLSQIKD LRLSPDTFKR
MNNLRFLKLY IPSGQSSGNM ILPTDLEPFS DKLRYFEWHQ YPFVSLPPSF YAKLLVEIRM
PHSQVKKLWE EKQYLEQLEQ ELNNLEGIDL SECKELEELP DLSEAKRLRW VNLSGCETLP
ILHSSVFSSN TLVSLILDRC TNLQCVKAER HLNSLQHISV KGCSNLKEFV VSSDLIENLD
LSNTKVEKLD KSIGKLQKVE CLNLEGSRVK HLPKELSALK SLKELKHSYS GLEIDKHQLQ
GLFNGLSSLQ ILHLKDCSHL FEFPDNIDSL SKLRELRLDG SNVTWLPATI KGLQELEILS
LNNCKFLETL PELPSSIKEF SADNCISLES VSALNTLATK MVGKTKRISF NNSLKLSAGH
TLHSIMESIH STMVSAVSSN VTVRSYAIDV HSYNYNSVEV CLPGDTIPEQ FAYKTEKSSS
ITIELPESPS NFLGFIYSVV LSPRHGMEKH GAKIRCEYNF AGGKNSSWED ITISELNSDH
VYIWYDPFLT DKILGQYGPS FHLEFSVATD TGEVDDSIII KECGVHIINE LELQRFLLEL
DKKKKDMEEE SSAQHLHFHP PHGSQDHSHV RTPPQDKKKG RFYEKQSNDI ENQISKRKRE
MNEQSSFDRK IEEKMESAPN ENKTSGGKSD EENTIKGKGN EETPTEPDAA LPLCIDSVKN
NVFQDISNEN YYDQPDSMEE AKHLEEKLQE VDHNVHDMTA DEPYKEKQGE PMDLETSECQ
DHTSNVEQTE NLGDAKKVQE LHKEKMIELA QPINSCIPPH GKKRAPKLTV KELRRHSRKV
DKKAKVEGNP ARATQATNLA METSDFSRSN IKGKRVDHIH LNQVPAQNAS TSIAQTHDKI
TIPSLDDPQV ALELLKHFDA SAKRLQITEF VDNHVLYPYD HSITKDLDVS ALCRWLQVQG
LRSVSVARYA EMKLEAAKRE REEELRLARE ENAKFEEALK RMEDRISHVE SLEKRVDDLN
SEVASWRSKY EETEKSLKET EKKLEDEKDV GAQKETRWKR RESELITEAA TCSFENCRSQ
VSILYPDIDL SRLGPFKEIQ NGQIVSPSDT EETESEEDTR AFEDAAHGDA GV
//
