ID A0A444YGM2_ARAHY Unreviewed; 765 AA.
AC A0A444YGM2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=Ahy_B06g079902 {ECO:0000313|EMBL:RYR01037.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR01037.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYR01037.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYR01037.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYR01037.1}.
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DR EMBL; SDMP01000016; RYR01037.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A444YGM2; -.
DR STRING; 3818.A0A444YGM2; -.
DR Proteomes; UP000289738; Chromosome b06.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF559; DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS) FAMILY; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000289738}.
FT DOMAIN 7..173
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 765 AA; 87116 MW; 31867B7C3414CE49 CRC64;
MAISTRWTNH VFLSFRGDDT RKGFTDHLFA SLERRGIKTF KDDHDLDKGG SISVELFKAI
EESMFALIIL SPNYASSTWC LDELQKILHC RSNLGQAVFP IFYGVDPSDV RYQRETFGEA
FRKHEERFRE DKDKVKRWRD ALKEVASFSG WDSKDQHEAG LVETIVDHIQ KLLIPKLPTC
TDNLVGVDSR IKRVISLIGM RLDDVRFVGI WGMGGIGKTT TARLVYESIK EEFQVSCFLQ
NIREMHEKNG LVQIQKELLS HLNVRSSNFH NFFDGKKIIA NSLCNKKVLL VLDDVSELSQ
LENLAEKQEW FGSGSKVIIT TRDKHILATH GVLKTCEIGG LFSNEALHLL SLKAFKQDQP
KEGYLDLCKE VVEYTKGLPL AIEVLGSHLH GRTIEVWHSA LKQIRSFPLP EIQNTLKVSY
DGLNSPEQDM FLDIACFFKG MDKEEVTDML ETCGGCPKIG IEILIERNLI TIGATNKLQM
HDLIQEMGRN IVFLESPNDP GKRSRLWSQD DIDHVLTNNK GTEAIQAIVL NIVQPYEACW
STEAFSNSNQ VRLLKLCQMQ LPLGLNCLPC SLKVLHWEGS PLKALPFSNQ LNELVDLNLS
HSKIEQLWHG KKGLSIPKAR FDMLITGSEI PSWFVPQRCI SFAKIAIPQN CPVNDWVGFA
LCFMLVSYAD PPQVCNHEVE CYLFGPKGKM FINSRNLPLM EPYCPHLYIL YLSIDKFRHT
IYEGGHFKEI EFVLKSYCCH SLQIVRCGSR LVCKQDVEDI FGNHS
//
