ID   A0A444YP67_ARAHY        Unreviewed;      1162 AA.
AC   A0A444YP67;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN   ORFNames=Ahy_B06g082883 {ECO:0000313|EMBL:RYR03692.1};
OS   Arachis hypogaea (Peanut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX   NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR03692.1, ECO:0000313|Proteomes:UP000289738};
RN   [1] {ECO:0000313|EMBL:RYR03692.1, ECO:0000313|Proteomes:UP000289738}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC   TISSUE=Leaves {ECO:0000313|EMBL:RYR03692.1};
RA   Chen X.;
RT   "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT   genome evolution and oil improvement.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RYR03692.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; SDMP01000016; RYR03692.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A444YP67; -.
DR   OrthoDB; 1386at2759; -.
DR   Proteomes; UP000289738; Chromosome b06.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR   CDD; cd00078; HECTc; 1.
DR   Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR044611; E3A/B/C-like.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   PANTHER; PTHR45700:SF9; E3 UBIQUITIN-PROTEIN LIGASE UPL7; 1.
DR   PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR   Pfam; PF00632; HECT; 1.
DR   SMART; SM00119; HECTc; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   PROSITE; PS50237; HECT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000289738};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00104}.
FT   DOMAIN          818..1162
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
FT   ACT_SITE        1130
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ   SEQUENCE   1162 AA;  131150 MW;  F1DA3394197BBBF9 CRC64;
     MDGTRKQQVS LRGASAKEIT RDVLLEKVNR ERELRNHAKR AAAAALLIQR VWRRFKVTKM
     VALQLQQEWE KLVNNYTAAR TAIWISNNLL RPFLFFITRF STWLQIAQSK KIHSMKICFT
     ILLESMNSSD SKQNFCFLAI GTPEERRIWI YQARRLTSLG FSILSEFSEC ISGAQNLNIV
     TSLAMRLLVM FTDPKGWKGI VDDNRQDADL AAKDLIQFIG SNKSGSYVSI ARYITALDNY
     SCQTKNIIPA DELFFITASA ITLAVRPFYL TNIDVIGPDM LDHNHATKQY IVYLLTIPSL
     LQHLPSVLQP ALRHKSILFP CFKTLLILKE KVLMEMSELV QSDNLVAFRE IPPVGWALTN
     IICLATGNEN GSVNARSLNQ GLDYALYVHV VITLAESLLA HLDNIGWMRK KRKTVQTDAG
     TSTDPVGTVM YDGEATYESL IMSYMDQFRP VTQLSHLTNL LASINRDGTN KVETPQSNRL
     PCLKKLDLFD VALFYSNLLR VFSTLSPIRG SLPVLNMLSF TPGFILQLWE VLEVSLFSGD
     KHISVYHTSG NAKHKTFEKI QKQISKDGGN RWVNVLQKFT GKSQAASDVT DPVGSYSEPS
     RENEDSLELW DVEPMRHGPQ GIPKDMFSVL HLFCATYSHL LSVLDDIEFY EKQVPFRLEQ
     QRRIASMLNT LVYNGLSHGS GSHNKPLMDC AIRCLHLMYE RDCRHPFCPP DLWLAPARKS
     RPPIAVAART HEVLSANLRF DDSSASLSAG SVIIITPHVF PFEERVEMFR ELIKMDKASR
     KMAGEISEPG SRAIEIVVCR GHIVEDGFRQ LNSLGSRLKS SIHVSFVSEC GLPEAGLDYG
     GLSKEFLTDL SKAAFAPEYG LFSQTSTSDR LLIPTESARY LDNGLQMIEF LGRIVGKALY
     EGILLDYSFS HVFVQKLLGR YSFLDELSTL DPELYRNVLY VKNYEGDVKE LCLDFTVTEE
     SFGKRHVIEL KSGGKDISVT NENKLQYIHA MADYKLNIQI LPLSNAFYRG LTDLISPSWL
     KLFNAGEFNQ LLSGGNYDID IDDLKNNTRY TGGYNEGSKT IKIFWEVVKG FKPDERCMLL
     KFVTSCSRAP LLGFKYLQPA FTIHKVACDV PLWTTFGGQD VDRLPSASTC YNTLKLPTYK
     RPGTLRTKLL YAITSNAGFE LS
//