ID   A0A445AYI0_ARAHY        Unreviewed;       811 AA.
AC   A0A445AYI0;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN   ORFNames=Ahy_B01g056307 {ECO:0000313|EMBL:RYR31505.1};
OS   Arachis hypogaea (Peanut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX   NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR31505.1, ECO:0000313|Proteomes:UP000289738};
RN   [1] {ECO:0000313|EMBL:RYR31505.1, ECO:0000313|Proteomes:UP000289738}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC   TISSUE=Leaves {ECO:0000313|EMBL:RYR31505.1};
RA   Chen X.;
RT   "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT   genome evolution and oil improvement.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC       transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC       {ECO:0000256|ARBA:ARBA00038341}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RYR31505.1}.
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DR   EMBL; SDMP01000011; RYR31505.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A445AYI0; -.
DR   STRING; 3818.A0A445AYI0; -.
DR   OrthoDB; 6504at2759; -.
DR   Proteomes; UP000289738; Chromosome b01.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   Gene3D; 3.40.50.12370; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR   PANTHER; PTHR32468:SF81; CATION_H(+) ANTIPORTER 19; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000289738};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        348..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          46..430
FT                   /note="Cation/H+ exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
SQ   SEQUENCE   811 AA;  87660 MW;  02AE56943DEB2D20 CRC64;
     MATPNPVTAA APPACPAPMK ATSNGAFHHE NPLDYALPLL IVQICIVVGF TRFLAFLCKP
     LRQPRVIAEI IGGLLLGPSA FGRNQKFLNT IFPKKSLTVL DTIANVGLLF FLFLVGLELD
     VRSIKRTGPK ALAIAVCGIT FPFLLGVGTS FVLRATISQG VQPLAFIVFM GVALSITAFP
     VLARILAELK LLTTDVGSIA MSAAAVNDVA AWILLALAIA VSGDNTSPII SLWVLLCGAG
     FILFAVYGIR PLLVIMAKHS LSGEPVKETY ICFTLTLVLA CSFLTDTIGI HALFGAFVVG
     IIVPKDGPFA GVLIEKIEDL VSGIFLPLYF VSSGLKTNVA TISGGTSWAL LALVIFNACF
     GKIVGTVVVS LSCKVPFRES LALGFLMNTK GLVELIVLNI GKDRKVLNDQ AFAICVLMAL
     FTTFITTPIV MAVYKPARRG APYKHKTIQR KDLDTELRML ACFHSTRSIP TLLNLIESSR
     GTKKFGKLCI YAMHLMELSE RSSAITMAHK ARRNGLPFWN NKPDDANGNN DHMIIAFQAY
     GKLNKVNVRP MTAISDLANI HEDICTSAHQ KRAAMIVLPF HKHQLVDGSM ESLGSSFRHM
     NELVLSHAPC SVGILVDRGL GGASQVQASD VSYNIVVLFF GGRDCREALS YGMRMAQHPG
     ISLTVVKFVT APGKSLAFGA KLVAVSVDKQ QKVVTEIDEN EKQLDEELWN EFLGKSIKYE
     ERLVDSRNDI EAALREMSRS SLILVGRMPS VAPLVYNSDS AQLGPVGSFL ASSEFSTTAS
     VVVIQQYNPA ADAHPLVMEE IDQLEEPDTP L
//