ID A0A445BG62_ARAHY Unreviewed; 1550 AA.
AC A0A445BG62;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA mismatch repair protein {ECO:0000256|PIRNR:PIRNR037677};
GN ORFNames=Ahy_A09g042475 {ECO:0000313|EMBL:RYR37611.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR37611.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYR37611.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYR37611.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|PIRNR:PIRNR037677}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family. MSH3
CC subfamily. {ECO:0000256|ARBA:ARBA00007094}.
CC -!- SIMILARITY: Belongs to the remorin family.
CC {ECO:0000256|ARBA:ARBA00005711}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYR37611.1}.
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DR EMBL; SDMP01000009; RYR37611.1; -; Genomic_DNA.
DR Proteomes; UP000289738; Chromosome a09.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:1901700; P:response to oxygen-containing compound; IEA:UniProt.
DR CDD; cd14824; Longin; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005516; Remorin_C.
DR InterPro; IPR005518; Remorin_N.
DR PANTHER; PTHR11361:SF122; DNA MISMATCH REPAIR PROTEIN MSH3; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF13774; Longin; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR Pfam; PF03763; Remorin_C; 1.
DR Pfam; PF03766; Remorin_N; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM01270; Longin; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR037677};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PIRNR:PIRNR037677};
KW DNA repair {ECO:0000256|PIRNR:PIRNR037677};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR037677};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR037677};
KW Reference proteome {ECO:0000313|Proteomes:UP000289738};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 179..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 294..358
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 101..132
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 23..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..463
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1550 AA; 173124 MW; 852B9A5212163CF3 CRC64;
MTEEEQPNKV DEEKSVIPQL PPPDNKHDDE SKALAIVEKT EEGAEEKPSE GSINRDAVLA
RVATEKRMSL IKAWEESEKS RTENKTQKKL SCISSWEKSK IASTEAELKK IHQQLEKKKA
EHAEKLRNKI AAIHREAEEK RAFTEAKKGE DILKAEETAA KYRATETAPK KIFALGHTYP
INAFVLLNNL VLVVLLLTNG FSNNQLKISC ITVIILTRTL ASSNYSSIHP FYLTKPYSNI
ITKQNKHGPV SNYLNGGCIY KIRNILVTSI ILLLLLIIRR VQETVSVVQE FYIFIRHIQI
FCLVENGVVF IVLCDSSYPR KLAFHYLQDL QKEFDKFNKT LIDNITRPYT FVKFDGIIAN
FSRQYIDTRT QANLSKLNAN RKQDLDIITE DMSNILERRR NSETLERSQV TPQPASSIWC
SPCLEQVISR FFAPKPKASP STTDPTPSSP PPSPLPSSSR PNPPTPKISA TVTFSPSKRL
LTSQIISPNK PPKLPKLSPH THNPLPHPTT HQRFLQKLLE PSEPEPPSHS SAKPLKYTPL
EQQVAELKGK YPDVLLMIEV GYRFRFFGQD AENAARVLGI YAHMDRNFLT ASIPTFRLNV
HVRRLVSAGY KVGVVRQTET AAIKAHGSNR LGPFCRGLSA LYTKATLEAA PDLGGGEEGC
GAESNYLMCV VEKSILGERS ACGVEGNFDV RIGFVAVEIS TGDVIYGEFD DNFLRSALEA
VMLNLSPAEL LLGDPLSKQT EKLLLAFAGP ASNVRVERTS RDCFADGGAL AEVLTLYENM
GIGCSSDSMQ NKDLTEHTNQ PLVKEVMNMP DLAVQSLALT IHHLKEFGFE RIVCSGFSLR
PFSRNMEMTF SANALQQLEI LKNNSDGSEN GSLLQIMNRT LTIFGSRLLR HWVSHPLCDQ
TMISARLHAV SEIAESMSSC SMKSLEYDED SDVTIVHPEL AYIVSLVLTN LSRAPDSQRG
VTRIFHCTAK PVEFVAVIQA ILSAGKQLQQ LNICEEENNN LRSNLLRRLI LTASSDSVIG
NATKMLSSLN KESADQGDLT NLIIASEAQF PEVTRARKAF QMEEEQLNSL IVLYRKRLGM
RKLEFMSVSG ITHLIELETD VKVPSNWVKV NNTKKTIRYH PPEVVTALDK VSLAKEELTI
ACRTAWDSFL RDFSKHYAEF QAAVQALAAL DCLHSLAILS RNKGYVRPVF VDDCEPVQIQ
ICAGQHPVLQ TTLQDNFVPN DTNLHADREY CQIVTGPNMG GKSCYIRQVA LIAIMAQVGS
FVPASSAKLH VLDRIYTRMG ASDSIQQGRS TFLEELSETS NILHNCTENS LVIIDELGRG
TSTHDGMAIA YATLHYLLKQ KRSIVLFVTH YPKIADLTTE FPGSVGAYHV SHLTSHHDTS
KNKNSYLDNI TYLYKLVPGV SERSFGFKVA QLAQLPPHCI TRGIFMASKL EELVNNRIHS
RSVKELLLDA IVIGQEQESH QEFGSAYKEL YSNLKAAILD DDHAKSFQLL DHSRKIAKKL
IGRWSGHNPI ASEKGPRVAM WRFRIDLLMA GDSFGIALRT ILRFVSACNM
//
