ID A0A445DVW6_ARAHY Unreviewed; 981 AA.
AC A0A445DVW6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Cation chloride cotransporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=Ahy_A03g013535 {ECO:0000313|EMBL:RYR67231.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR67231.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYR67231.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYR67231.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYR67231.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SDMP01000003; RYR67231.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445DVW6; -.
DR STRING; 3818.A0A445DVW6; -.
DR Proteomes; UP000289738; Chromosome a03.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF100; CATION-CHLORIDE COTRANSPORTER 1; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000289738};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 142..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 143..608
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 652..773
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 784..980
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 981 AA; 107313 MW; B3193ACED2F47E06 CRC64;
MEDVDLDGGG GSGRKYRPVL DSDRAVLEMS SMDPGSSSAA SSSQPFRDQP PPNLRKINVG
NGATEASNAK EGNNSPSQPQ PNGSHQESKL ELFGFDSLVN ILGLKSMTSE QAVQPSSPRE
GEDISITVGE PKPAAPKLGT MMGVFIPCIQ SILGIIYYIR FSWIVGMAGI GESFLLVALC
GLCTFLTSIS LSAIATNGAM KGGGPYYLIG RALGPEVGVS IGICFFLGNA VAGALYVLGA
VETFLKAVPK AGIFRETVSH VNGTAVTPIE APSSHDLQIY GIVVTILLCF IVFGGVKMIN
RVAPAFLVPV LFSVICIFLG MFVAKKDKPS EGFTGLSWET IKDNWSSDYQ KTNDAGIPET
DGHVSWNFNS LVGLFFPAVT GIMAGSNRSA SLKDTQRSIP IGTLSATLIT TSLYFISVLF
FGAVATREKL LTDRLLTATV AWPFPSLIKI GIILSTLGAA LQSLTGAPRL LAAIANDDIL
PILRYFKVAD GSEPYAATLF TAILCGVCVI IGNLDLITPT ITMFFLLCYT GVNLSCFLLD
LLDAPSWRPR WKFHHWFLSL VGALLCIVIM FLISWSFTVV ALALASLIYK YVGLKGKAGD
WGDGFKSAYF QLALRSLRSL GENQVHPKNW YPIPLVFCRP WGQLPENVPC HPKLADFANC
MKKKGRGMSI FVSILDGDYH ECAEDAKTAC KQLSTYINYK NCEGVAEIVV APNMSEGFRG
IVQTMGLGNL KPNIVVMRYP EIWRRENLTE IPKTFVGIIN DCIVANKAVV IVKGLDEWPN
EYQKQYGTID LYWIVRDGGL MLLLSQLLLT KDSFESCKIQ VFCIAEEDAD AEVLKADVRK
FLYDLRMQAE VFVIPISSQE NGGSPQDESH DAFKGAQQRI DDYLNKMKAA AKKDGTPLMA
DGKRAVVNEQ QVEKFLFTTL KLNSIMLRYS RMAAVVLVSL PPPPLNHPAY FYMEYMDMLL
ENIPRILIVR GYRRDVVTLF T
//
