ID A0A445E2U6_ARAHY Unreviewed; 1222 AA.
AC A0A445E2U6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=Ahy_A03g016291 {ECO:0000313|EMBL:RYR69742.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR69742.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYR69742.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYR69742.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYR69742.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SDMP01000003; RYR69742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445E2U6; -.
DR STRING; 3818.A0A445E2U6; -.
DR Proteomes; UP000289738; Chromosome a03.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF252; RESISTANCE PROTEIN (TIR-NBS-LRR CLASS), PUTATIVE-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000289738}.
FT DOMAIN 1..133
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1138..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1165..1181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1184..1198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1204..1222
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1222 AA; 139104 MW; 9E5A69BA9C88B865 CRC64;
MDDEYLTEGE TIRPQLLKAI EDSKVSIVVF SENYATSAWC LDELVKIFQC HKEKNQLVFP
IFYKVDPSDV RHQNNSYKQA MDAHEIRYCY ESQKVQKWKE TLAEISNMKG FHLKQGYEFE
FIQDIVNKIS TKVSAKQLPI EEHVVGLQYQ VARLKSILDI ESNDNTFMLG ILGIGGIGKT
TLAKALYNSL CNQFEGACFL FNVRETSSQE KGKVCLQQML LSKILQKGKV KLGSVDEGIS
TLKERLCTKR VLIVLDDVDK IEQLQALAGG CAWFGSGSRI IITTRDKYLL AVHQVKRIYD
MPMLNEHDSL QLFCQNAFKT SSPPTNYEDM CNRAIRYAKG LALALKVIGS NLIDKDLKEG
KSALDKYEKN PHIDIQSILR ISYDSLQHNE KEIFLDIACF FNGMRLDYVK RILDGCGFYS
EDGIRILIDK SLIAIEHGYL RMHDLIKDMG RDIVKQEAPK EAGERSRLWF REDVLEVLTK
NTGSAKIEGI KLDLPEGVNW SDTVFKKMKK LRILIVRNTS FPSWPIYLPN QLKLLDWKGY
PSKFLPPGFY PEQIAAFNLR FSLLVLKKPF QKFEHLTYMN FSCCQSITKF PDVSGAKSLR
ELILDGCKKL VKVDDSIGFL PNLVYLSASE CTQLKSFLLQ ISLPSLEYLS FDLCSRLAHF
PDVLGKNDKP LKISLRHTAL RELSDSFAEL SGLGYLDMTG CKELKYLPSS LFMLPNFVTL
KIGGCSQLRE LLTSSKGRLS EAEHRPKLET LDFSNACLSN EDLHVIMQSF PNLKDLNVLS
NYFVSCPESI KESICLRSLD VSYCLKLQEI PELPSNVQKL NARHCNSLTA DTSSMLWSQV
CKEINKLQVL MPQTDIPDWF DYHDQGGIPI FWARCKFPAV ALAFMFGKMN YQAVELHLFI
DSEHVNVQHQ HKHTLNIAEN HVLLCDLRAF FNDEEWESLD ARIGHDNNWK QVQVVCEPDT
SLREWGVYVY KKETNMNDIQ FTCPYHESSR LQSLLVITNT KTISREDDME IESARASASS
VEETSASIVQ ALEASYSKHG VPHVNSNSWA QTCSLCCSAL LSSYRRLLCC TCRCRIDDDE
PCGEARMTKA QPARLMLDDN LNCCAQTCCL CFSALLSSFR RLLCSIYGRR LDNDEPYGEV
KMTKAQPGPM ISRPQEESTE NVDEERVPSS FSQSLQTVVE NLKRLTAPRE DKGWSHGEDS
YNSELSDVDF EDDGEGNLDM EA
//
