ID A0A445EM89_ARAHY Unreviewed; 5097 AA.
AC A0A445EM89;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Ahy_A01g001140 {ECO:0000313|EMBL:RYR76558.1};
OS Arachis hypogaea (Peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=3818 {ECO:0000313|EMBL:RYR76558.1, ECO:0000313|Proteomes:UP000289738};
RN [1] {ECO:0000313|EMBL:RYR76558.1, ECO:0000313|Proteomes:UP000289738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Fuhuasheng {ECO:0000313|Proteomes:UP000289738};
RC TISSUE=Leaves {ECO:0000313|EMBL:RYR76558.1};
RA Chen X.;
RT "Sequencing of cultivated peanut Arachis hypogaea provides insights into
RT genome evolution and oil improvement.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYR76558.1}.
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DR EMBL; SDMP01000001; RYR76558.1; -; Genomic_DNA.
DR Proteomes; UP000289738; Chromosome a01.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 1.
DR CDD; cd21134; YTH; 1.
DR Gene3D; 3.10.590.10; ph1033 like domains; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR030380; SAM_MeTfrase_DRM.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR InterPro; IPR009291; Vps62.
DR InterPro; IPR007275; YTH_domain.
DR PANTHER; PTHR45523:SF6; SHR-BD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45523; TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
DR Pfam; PF06101; Vps62; 2.
DR Pfam; PF04146; YTH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51680; SAM_MT_DRM; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50882; YTH; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000289738};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 326..467
FT /note="YTH"
FT /evidence="ECO:0000259|PROSITE:PS50882"
FT DOMAIN 875..923
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 1051..1377
FT /note="SAM-dependent MTase DRM-type"
FT /evidence="ECO:0000259|PROSITE:PS51680"
FT DOMAIN 1715..1825
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 260..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2088..2111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2088..2104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5097 AA; 568325 MW; 9FCB76C74367C03B CRC64;
MEMHDVSENR STDAYLIEGT GLNPQLTSPN FQQFEAMFSE GAPEFIVDQN LYYPSATNYG
YYCTGFESPV EWEDHHRIFG VDGPEIQYMG AQNESFPYVY YTPSYGYAQS PYNPYNPYIP
GAMMGVDGSF GGAQHYYSLP SYQNPVSSPG YIPFVVPPDN LPDSFVDPLI DTSASVSKPD
GRGFKHKFNS VSGAFTKNSS KPLSNQASSL ARVLEGPRAN AGVKKDSNIG SVSGSGFLNM
TPSPIHESAS AKLRPKFHVG KVPSDVNSNT DVLGEQNRGP RISRSKHQLS VKAYTTKAGD
GNTHGNIIIY TDQYNREDFP LEYENANFFV IKSYSEDDVH KSIKYNVWSS TPHGNKKLES
AYEDAKRIAA GKSGGCPIFL FFSVNASGQF CGVAEMVGSV DFNKDMDFWQ QDKWSGSFPV
KWHIIKDVPN GSFRHIILEN NESKPVTNSR DTQEIMYKKG LEMLKIFKSH TLKTTLLDDF
MYYENRQKIM QEEKAKLLIK SFQNPLLMPT MEPPRKLNFV VDVPQVNDEK NSKTDDKFDR
LVSSVKETVQ SSDVTSTKST NEKAEKTTAD KEDISSILKI GSVSITPKQG ETKPSSIGVS
DREPVDIVTV GSMQVKVNGF SESSSVLKVG SIPLDRKALQ LDKGTAYECD HAPSPLHPVR
VGKPTLNSTE HSSVAVAMAG SSNRREGKNA MVPKPELLDF DVELQPPYAT FSGNVGDNVA
SSSGSQLRSF FVGMGFQPSL VDKAIEENGD QNSDRLLEVL LSYSALQKSN SESSDSLESL
FDDKDSPEIS TVNQPKEELD EFGEFIDDKR SSLLMMNFSA EEVDFAISKL GDGASVPELV
DFIFAAQIAK KLNRETVHIK RETIDITCDD TGGETSNERL FGIMEKTLQL LEMGFSENEV
SSAVDRLGTE VPISELANYI FAEQSGIEYV MEYKYPFTSM YSMGIKEEQQ WDGTAEVKTE
FFGYEAPQSG PINFRGTFSD RGKRVKEEGI DEFANGASDM GYSDFMENDR SKRPKNEYEE
DESSSFLDIY WMEERVDAQV ARMTELHRSK PARTLSDIAA KSPFFLFGNV SNISYESWTK
MSQFLYVEPE FVNTRFFSAL NRIEGYLHNL PFEGRTHILP KPPLTIEETM PRTTKWWPSW
DSRKQLSSIC CETNGISRHC EWIGKILADS GGVPTPEQQE DIVRSCRILN LVWTGQYKLS
PVEPDKLEFI LGYPLDHTSA VCNLAERLEL LKYCFQTDTL GYHLSVLKPL FPNGLTVLSI
FSGIGGAEIA LHRLGIKMKA VVSVETSEAK RKILERWWRV SGQKGNLVQM EEVQKLTSKT
LQGLINKFGV FDLVIYQHPN SYASSRIDPT GRHPAFDFSF VESVRLLQRV LHLLRRYLGE
YVHGLSQETL RISVWNGDVV LKDLRLKAEA LNSLKLPVTV KAGFVGSITL KVPWKRLGKE
PVIVLIDRVF VLAQPVPDRR TMKEEDREKL FQAKLQQIEE LESATLDAIS KSKFVKRSKA
VSPTVALETA TALQMKIEKV TRRAQEQFQM VLEEKSRFAF DVDLDAPKVR IPLRSRGSAR
CDSHFLLDFG HFTLHTAESQ SDEQRHNLYS RFYISGRDFA AFFTDCGSDF GSCSLVKPTH
DSQIISSPRA KEADNVYSVI DRCGMAVLVN QIKVPHPSYP STCISIQVPN LCIQFSPERF
CRIMELLSIL RKTMETCNQP TPDSLHSKLA PWSRDLVVDG RILVWKGIGN SVATWQTCFL
VLSGSYLYVF ETAESQSYQR YLSMAGKQVL EVPPTNVGGS PFCIAISSRG MDFQKALESS
STWILDFREE KEKARWFKRL IQATYEASAP LSVDVLDDSN SDAACDNVLN TSKKSADIVI
NGALVETKLL IYGKAGDTLD GKFGESLMLE VIADGGKMHL ALANADLTMK MKLHSLKVKD
ELQARLSVTP QYLAVSVLKE SVSSSPSALF DSHGKDASLG FPDDDDSFSD ALSDFISHVE
GGNHLHNMDL DMQGGMGIAS DFESLESLIH EKEIEKGKYT PREVYYEAEG TDNLHFVSVT
FATRSSSSPD YDGIDTQMCV RMSKLEFFCN RPTILALISF GLDISSGNKG KSDTSTIATS
PEQTSMKKDK TDEKERVKGL LGFGKERVVF HLNMNVDSVT IFLNKEDGSQ LATLVQENFL
VDLKVHPSSL SICGTLGNFR LRDTCLGPEQ CWDWLCDIRN PGVESLIKFK FNSYSAGDDD
YEGYAYKLQG QLSAVRIVFL NRFVQEIMVY FMELATPRTE EAIKLVDKVG GFEWLIKKHE
IDGATALKLD LLLDTPIIIF PRDSLSKKWH GSREEDPSAV HIDILHAQIL GINMSVGIDG
CLGKPMIREG QGFDIFVRRS LRDVFRKVPN FSLEVKVDLL HVIMSDKEYK VILDCTCWNL
REPPRLPASF RGGSSDSKDT IKLLVDKVNT NSQQLLSQTV TIMAVVVNHA LLELCNGTET
DLFVTIPKFS ILDVRPDTKP EMRLMLGSST DASKQSVTGK VPFALNTGSF RRTISDTGVD
VDMPISTMFL MDCRWRTSSQ SFVIRVQQPR VLVVPDFLLA VAEFFVPALG ALTGREETMD
PKNDPISRNN SIVLMESIYK QKEDVVYLSP SKQLVVDHVG VDEYIYDGCG KVICLSVETD
TKEARTVRFR PIIVIGHGKK LRFVNVKIEN GSLLRKYTYL SNDSSYSVSI DDGVDIVAPD
ILSSGDEKSL DNMNQMSSTY TDSQSESEMT RSFTFETQVV SSELTFYDGT KSFLDDSSYG
EKLIRAKLDM SFMYASKGKD SWIRTLVKDF TLEAGSGLVI LDPVDISGGY TSVKDKTNIS
LLSTDICVHL SLSAATLILN LQSQASAALS FGNATPLVQC SNYDRIWVSE KETGPNKNIT
FWRARAPSNY VVLGDCVTSR PIPPSQAVMA VSNTYGRVRK PVDFYLIGSL LKILGHDGPD
GHSISGSDCS LWMPIPPPGY VALGCVAHTG NQPPPKHVVH CLRSDLVTSA EYSDCLHNIP
SNEQFTSVFS IWRLDNAVGS FFAHFSTGCP LKDSCYDLNH LLLWNSNRAP LMDPFSSFNS
DNEDIEDTRK SVTTSGWDIV KSISKAANSY ISTPNFERIW WDKGGDLRHP VSIWRPIARH
GYAVVGDCIT EGLEPPALGI VFKSDNPDLS SKPVQFTKVS HILGKGIEEV FFWYPIPPPG
YVSLGCVVSR TNEPPSADLF CCPRMDLVSQ ANIHEVPLSR SSSSRAPQCW SIWKVENQAC
TFLARSDLKK PSSRLAYIIG DSVKPKTREN INAELKLRYF SLTILDSLYG MMRPLFDTTI
TNIKLATHGG LEGMNAVLIS SIVASAFNAK LEAWEPFVEP FDGIFKFESY DTNVQSEFGV
GKRIRMSATS ILNVNISAAS LDTFVGSILS WRRQMELEEK ASKLNMEAGD QQSKGEDTAF
SALDEDDLQT VVVENNLGCD IFVKKVEHNV NTVDKLNHGD CASVWIPPPR FSNRLNVADE
SREARYYVAV HILEAKVGLS LIDDGNSHNF FCALRLVVDS QASEQQKLFP QSARTKCVKP
VVSQSDQDEG TVKWNELFIF EVPRKAPAKL EVEVTNLAAK AGKGDVVGAL SFPVGHGANI
LRKVASTRMF HQSYDVQSIR SYPLSKMVQH SNAEAINEGF LYVSTSYFER NTIAKHQKDM
ESLNDVDREI GFWVGLGQEG EWESIRSLLP LSVVPKSLEN EYVAMEVLMK NGKKHVIFRG
LVTVVNDSDV TMNILTSRSS HGIDPSPGAY SSNTVVEEVF QNQYYQPSYG WSNNWPLTEH
DAPGHWSTRD FSYSSKDFFE PPLPPGWKWT SGWSIDKFQY VDKEGWAYGP DLKNLQWPPT
SSTFSTKSSS DVVRRRRWIR TRQNFSDQGK EYIQSGASTL HPGASTVLPL RSTSKNSNHY
LQVQPNSNGS MPSYSWGCAV AVGSTYMYSK DQPVDQSSRR NSATSNCSMN LNELEKKDIL
LCCNPSSGSK QLWLSVGIDA TVLNTELNAP VYDWRVSVNS PIKLENRLPC PAEFSISEKT
KEGNCVEQHQ GVVSSRQSVH IYSADIRKPL YLTLFVKGGW VMDKDAILVL DPSFSNHVSS
FWMVHPKSRR RLRLSIELDM GETSTAPKTL RLFVPYWIVN DSSLLLAYRV VDVEALENTE
ADSVLLSRAA KSARTALKNP ISSLDRRHSN SRGNLQVLEV IEDSSPFPSM LSPQDYAGHS
GAAMFQSQKD AYLSPRVGLS VSLRHSEIYS SGISLLELEN KERIDVKAFN SDGSYYKLSA
LLNMTSDRTK VVHFQPHTIF INRVGCSVCL QQCDTQSALW IHPDDPPKPF GWQTSAKVEL
LKLHVDGYKW SAPFSVSYEG VMRISLNKEA GGDPMQLRVA VRTGAKKSRF EVIFRANSLR
SPYRIENRSM FLPIRFRQVD GTADSWQLLL PNSAASFLWE DLGRRRLLEL FEDGTDPMKS
LKYDIDEVAD HQPTQTGDGP TKAMRVTILK EEKINVVKIS DWMPETEPAG VLGKRHLSAM
SESQKQQLTA ISNSEFHINF DLAELGISII DHTPEEILYL SVQNLVLAYS TGLGSGISRF
KLRMGGLQVD NQLPLTPMPV LFRPQRLVAE IDYILKFSVT MQSDGSLDLC VYPYIGLHGP
EGSAFLINIH EPIIWRLHEM IQVVKLGRLT DSQTTAASVD PIIQIGVLNI SEIRFKVSMT
MSPSQRPRGV LGFWASLMTA LGNMENMPVK INQKFHENVC MRQSSMISMA VSNIRKDLLG
QPLQLLSGVD ILGNASSALG HMSKGVAALS MDKKFIQSRM RQESKGVEDF GDVLREGGGA
LAKGLFRGVT GILTKPLEGA KSSGVEGFVQ GVGKGIIGAA AQPVSGVLDL LSKTTEGANA
MRMKIASAIT SEEQLLRRRL PRVIGGDNLL RLYDEYKAQG QVILQLAESG SFFSQVDLFK
VRGKFALTDA YEDHFMLRKG KILMITHRRL ILLQQPSNVI GQRKFIPARD PCSIQWDIRW
DDLATMELTH GKKDNPKSPP TRLILYLKSR TLDTKENVRI VKCIPESHQA LEVYSSIDRA
FHTYGPGASK VTLAKNAKKP YSPHVEGSKV DLTLKEVTPG STPVSSIFGS SSSRRYS
//
