ID A0A445G8Y8_GLYSO Unreviewed; 1072 AA.
AC A0A445G8Y8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=D0Y65_046366 {ECO:0000313|EMBL:RZB57663.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:RZB57663.1, ECO:0000313|Proteomes:UP000289340};
RN [1] {ECO:0000313|EMBL:RZB57663.1, ECO:0000313|Proteomes:UP000289340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZB57663.1};
RA Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT "A high-quality reference genome of wild soybean provides a powerful tool
RT to mine soybean genomes.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZB57663.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QZWG01000017; RZB57663.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445G8Y8; -.
DR Proteomes; UP000289340; Chromosome 17.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR PANTHER; PTHR45786:SF66; REPLICATION FACTOR-A CARBOXY-TERMINAL DOMAIN PROTEIN; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044, ECO:0000313|EMBL:RZB57663.1};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000289340}.
FT DOMAIN 181..349
FT /note="Helitron helicase-like"
FT /evidence="ECO:0000259|Pfam:PF14214"
FT DOMAIN 804..850
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 1072 AA; 124005 MW; 50B574CC4447DD4F CRC64;
MMKIANPILM KLQSILKTIS DYFDLGDQAM QCRHCNAKMC QHVGIQPEIV STLSQMLDEY
NVHAKSFRMA RDRLADTQVD NVKLRLIATR EKDGHTYNLL NVSEVAALIV GDFDSDSRRD
IIVETQNGEL QRIHELHCSY LGLQYPLLFP YGEDGYRPDI LHRCTPSSRK RKRNRLTMRE
WFAYRLQSRS NEAQTLLHSR KLFQQFIVET YTMVESERLS YIRNNKKKLR ADKYCSLQTS
LDAGSSKGSS KGKRVILSST FVGSPRYMDQ LYFDGMAICS HVGFPNLFIT LTCNPNWPEI
RRVLAPLNLK ATDRPDLISR VFRLKYEHML FDLTKKHLLG KVVACYDRVT AVVIHDANGT
LENAISQNDE IKEYVDCRYI SPCEATWRIF GFPIHARKPV VERLHFHLLG QHSVFYEDDD
DIDDILSKPS ISDSKFLAWM NSNKCFLEGR NLTYSQFVSK FVYNQKARSW NLRKKGNTIG
RLIWVPPTTG ELFYLRMMLT ACKGATSFED IRTVENVLYL TYREACFAMG FLQDDREFME
AIKEAKDWES HIDDEQLKNL TLLEIEKLLH PNQRSLRDYP TMPYPEGGNP ASCLKNSLIL
SELNYNNDEA RSEFKNLFLS MTDEQKQIYH KIMEAVNNNE GGMFFLYGYG DTGETYIWRT
LASSLRAKNQ IVIMVASSGN AQLIDDQETT KFAKWILDIG DGVIGNQNDG YATIEIPEYL
LITEYNDPID AIVKSTFPDL YQHHSNPEFF KSRAILASTN ETVEKVNDYI LSLIPGEQME
YLSSDYIEKS ETIDSWHFQS ITTEFLNSLN TSGLPNHRIK LKIGSPIMLL RNLDQTQGLC
NGTRLIVTRL AKHVITAEII SSKNVGDNVY IPRMSMSPSQ SPWPFKLLRR QFPIMLSYAM
TINKSQGQSL SMVGLYLPKP VFSHGQLYVA LSRVNSRQGL KVLIHDKDQK NMTSTTNVVF
KEVFKNLIRQ RHSSRKHMWT LQLTQEMLDH PEPLSLLQPQ DSLKAAWPPL QWKVETLNPA
IGEKGVVQPW YDFLEEMNFD DGDEISIYYR YYEKIWDIII RRQEDWEDDD SD
//
