ID A0A445HZ25_GLYSO Unreviewed; 1015 AA.
AC A0A445HZ25;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=DNA mismatch repair protein MLH3 isoform A {ECO:0000313|EMBL:RZB78966.1};
DE Flags: Fragment;
GN ORFNames=D0Y65_029370 {ECO:0000313|EMBL:RZB78966.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:RZB78966.1, ECO:0000313|Proteomes:UP000289340};
RN [1] {ECO:0000313|EMBL:RZB78966.1, ECO:0000313|Proteomes:UP000289340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZB78966.1};
RA Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT "A high-quality reference genome of wild soybean provides a powerful tool
RT to mine soybean genomes.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZB78966.1}.
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DR EMBL; QZWG01000011; RZB78966.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445HZ25; -.
DR Proteomes; UP000289340; Chromosome 11.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 2.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR014790; MutL_C.
DR InterPro; IPR042120; MutL_C_dimsub.
DR InterPro; IPR037198; MutL_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF47; DNA MISMATCH REPAIR PROTEIN MLH3; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF08676; MutL_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SMART; SM00853; MutL_C; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF118116; DNA mismatch repair protein MutL; 2.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000289340}.
FT DOMAIN 242..387
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT DOMAIN 789..937
FT /note="MutL C-terminal dimerisation"
FT /evidence="ECO:0000259|SMART:SM00853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RZB78966.1"
SQ SEQUENCE 1015 AA; 113714 MW; 25548C7DD13F0A99 CRC64;
SRRGEEPIGH VHPNRSGGGG LMASIKLLSE AVRSSLRSGI FLVDFTRVVE ELVFNSLDAR
ATKGETEKLK VSVFVSTGSC YLKVVDDGSG IPRDGMEMVG ERYATSKFLN LVDLNASSEN
FGFRGEVLAS ISEVSLLEIV TKTYGRPNGY RKVLKGCKCL YLGIDDDRKE MGTTVVIRDL
FYNQPVQRKY MQSSPNKVLQ SIKNCVVWLA LVCPNISFKV VDIEREDELF CTHSASSPLS
LVTSGFGVEV TSSLHNLEVE NDIIKLSGYI SGPCNTVDTK VTHISNLKSL AVCLYPYANS
QFVCKGPVHK LMRQLANRFE HLNSWNTDEE FQNKKRTRCQ PCPAYLLNLS CPRSLYDLAF
EPSKTVKFKD WAPILNFIVK AIKQFWEENV ACDPSNGATY MVEDQHHFSS IREDVDYLGV
TIFKEKQSKG DFLLQTGYSG NLLDGSYAKC TSTVMRKHNS LLMHNSNSLL EGDNFFDGEI
PAVESFNIDV PFDAPSSSHG RRFHKVEADV INESFEDDLL YNSCSGYGYD VKINEDLQQP
FLKRCSTLGS ILHEKALFVN DEYELQTDSF WSKQNAEEDY RSGKDLYAHP CPEVTKKLKM
SKDSDFLVRA LSEENCLPPD LCYSALQIGS SGSDDQLLNF EWHPDYQKPS SQASALEASN
FKYPQQSPVG LHHSTEEFLL QEFKINVKRT SEVLGDMQVN DITDIDGFES FNIQNSAPFG
ELISRGVQDS LDYGTKWRNC SPKITKNDKL ANIQSQNNIL DISSGFLHLA GDSLIPETIS
KKCLEDAKVL HQVDKKFILV VAGRTLAVID QHAADERIRL EELCQKVLSG EAKAITYLGA
EQELVCIYEL ENLMYCRRLV INYFIVIVKR LKTGAESAPF MLKILNPLEG VKLNDVDLLE
FLQQVADTDG SSTMPPSVLR VLNLKACRGA IMFGDSLLPS ECSFIVEELK HTSLCFQCAH
GRPATVPLVN LEALHNQIAK LRLMNECSSD ECHGLRRHTV RVERAAQRLN SARGI
//
