ID   A0A445JLW0_GLYSO        Unreviewed;       923 AA.
AC   A0A445JLW0;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE            EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN   ORFNames=D0Y65_022057 {ECO:0000313|EMBL:RZB99452.1};
OS   Glycine soja (Wild soybean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3848 {ECO:0000313|EMBL:RZB99452.1, ECO:0000313|Proteomes:UP000289340};
RN   [1] {ECO:0000313|EMBL:RZB99452.1, ECO:0000313|Proteomes:UP000289340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC   TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZB99452.1};
RA   Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT   "A high-quality reference genome of wild soybean provides a powerful tool
RT   to mine soybean genomes.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC       from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RZB99452.1}.
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DR   EMBL; QZWG01000008; RZB99452.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A445JLW0; -.
DR   UniPathway; UPA00591; UER00663.
DR   Proteomes; UP000289340; Chromosome 8.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   CDD; cd01319; AMPD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 3.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR006329; AMPD.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR   PANTHER; PTHR11359:SF14; AMP DEAMINASE; 1.
DR   Pfam; PF19326; AMP_deaminase; 2.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:RZB99452.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000289340};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          51..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   923 AA;  105712 MW;  6665AEDD8BD4A4FA CRC64;
     MDPSSSLPPS LHLAMAALLG ASFMALSAFF IHRRTVDHVL HRLVELRRKP LATSSDDSDD
     DDDDRTGFGD DNGDTETDAD LRSYRGTLSM SVDDSSNVLR SYRISSSMPN VVSATDWIRE
     DAKNRASSLE NLQFVPSGLP SLRTGSNNGE SVQVLCSYKR IGSVGRIMTP RSPGRTTFES
     AEDSDEEEIQ LADDNRIPFS NTYGLDSNVC NLPAVPFRVE DANNQMYGEA SKEVKAGADM
     NGHGITDSTP VHVAGDDIVF ANNVLPTRNT VHETTNIEEE EVCKMIRECL DLRKKYVYKD
     VPWKTEPVET NSDPYHFEPV EATSHHFRME DGVIHVYASK TDTEELFPVA SSTRFFTDMH
     YILKVMSIGN VRTSCYHRLR FLEEKFRLHL LLNADREFLA QKGAPHRDFY NIRKVDTHIH
     HSACMNQKHL VRFIKSKLRK ESDEVVIFRD GKYMTLKEVF ESLDLTGYDL NVDLLDVHAD
     KSTFHRFDKF NLKYNPCGQS RLREIFLKQD NLIQGRFLAE VTKEVLTDLE ASKYQMAEYR
     ISVYGRKQSE WGQLASWFVN NALYSKNAVW LIQLPRLYNV YKNMGIVTSF QNILDNVFIP
     LFEVTVDPNS HPQLHLFLKQ VVGFDLVDDE SKPERRPTKH MPTPAEWTNE FNPAYSYYLY
     YCYANLYTLN KFEVGWVLFL FLVGCGEVEV FKFKHINGKK ETGKDGANRD LQKNSWLSTI
     LISHCWFQLR ESKGMTTIKL RPHCGEAGDS DHLAAAFLLC HNISHGINLR KTPVLQYLYY
     LAQVGLAMSP LSNNSLFLDY KRNPLPMFFQ RGLNVSLSTD DPLQIHLTKE PLLEEYSVAA
     KVWKLSACDL CEIARNSVYQ SGFSHQAKSH WLGDKYLFRG SEGNDIHKTN VPNLRISFRY
     ETWKEEMQFI YAGQAVFLED VDP
//