ID A0A445LJM9_GLYSO Unreviewed; 1012 AA.
AC A0A445LJM9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
GN ORFNames=D0Y65_002980 {ECO:0000313|EMBL:RZC23423.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:RZC23423.1, ECO:0000313|Proteomes:UP000289340};
RN [1] {ECO:0000313|EMBL:RZC23423.1, ECO:0000313|Proteomes:UP000289340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZC23423.1};
RA Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT "A high-quality reference genome of wild soybean provides a powerful tool
RT to mine soybean genomes.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361199};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZC23423.1}.
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DR EMBL; QZWG01000002; RZC23423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445LJM9; -.
DR OrthoDB; 5474711at2759; -.
DR Proteomes; UP000289340; Chromosome 2.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10810; GH38N_AMII_LAM_like; 1.
DR Gene3D; 2.60.40.1360; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR048534; Man2a1-like_dom.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF61; ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR Pfam; PF21260; Laman-like_dom; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW Hydrolase {ECO:0000256|RuleBase:RU361199};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361199};
KW Reference proteome {ECO:0000313|Proteomes:UP000289340};
KW Signal {ECO:0000256|RuleBase:RU361199};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT CHAIN 26..1012
FT /note="Alpha-mannosidase"
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT /id="PRO_5018811050"
FT DOMAIN 361..435
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1012 AA; 114026 MW; 3F46B649BAAC1468 CRC64;
MGNLAAESLC ALLLLYFYGT LLVSAKYIKY NTGAGVVPGK LNVHLVPHSH DDVGWLKTVD
QYYVGSNNSI QGACVENVLD SVVVSLQKDP NRKFVFVEMA FFYRWWVEQS PETQEQVKKL
VDEGQLEFIN GGWCMHDEAA THYIDMIDQT TLGHRFIKDR FNKTPTVGWQ IDPFGHSAVQ
AYLLGAELGF DSIHFARIDY QDRAKRKADK SLEVVWRGSK TFGSSSQIFA NTFPVHYSAP
NGFNFEVNNP DVDVVPVQDD PLIFDYNVEQ RVQDFIDAAT TQANVTRTNH IMWTMGDDFQ
YQYAESWFKQ MDKLIHYVNK DGRVNALYST PSIYTNAKNA ANQTWPLKTD DYFPYADSRN
AYWTGYFTSR PALKRYVRML SGYYLTARQL EFLVGKKSTK YNTYDLGDAL GIAQHHDAVS
GTAKQHTTND YAKRLAIGAS EAEAVVSSSL ACLTRKQSGD KCSAPASAFA QCQLLNISYC
PPAEDNIPEA KSLVVVVYNP LGWNRTDIVK IPVNDANLVV KDSSGNNLEV QYVDVDDVTT
NLRKFYVKAY LGVSPKQAPK YWLLFQVSVP PLGWSTYFIS KATRKGTRRK DLSHPNSQKG
DTINVGSGNL KMSFSSTSGQ LKRMYDSKTG VDLPIQQSYL WYGSSEGDSD PQASGAYIFR
PNGSPPNIVS RSVPTKVIRG PLVDEVHQKF SSWIYQVTRL YKDKDHAEIE FTIGPIPTDD
GVGKEVITRM TANMATNKEF YTDSNGRDFL KRVRDHREDW PLQVTQPVAG NYYPINLGIY
TKDKKSEFSV LVDRATGGAS IKDGEVELML HRRILHDDSR GVGEPLDEQV CVNNNNTCEG
LTVRGNYYIS IHKLGAGSRW RRTTGQEIYS PFLVAFTHEN SENWKSSHLT KGTIMDPNYS
LPPNIALITL EELDGGIVLL RLAHLYEPSE DAEYSTLTKV ELKKLFAMKT IKELKEVSLS
SNQEKSEMKR MTWKVEGDKG QEPLAIRGGP VSYHNLVVEL GPMEIRTFLL KF
//
