ID   A0A445LS06_GLYSO        Unreviewed;       431 AA.
AC   A0A445LS06;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 10.
DE   SubName: Full=UDP-glucuronate 4-epimerase 1 {ECO:0000313|EMBL:RZC25984.1};
GN   ORFNames=D0Y65_004596 {ECO:0000313|EMBL:RZC25984.1};
OS   Glycine soja (Wild soybean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC   Glycine subgen. Soja.
OX   NCBI_TaxID=3848 {ECO:0000313|EMBL:RZC25984.1, ECO:0000313|Proteomes:UP000289340};
RN   [1] {ECO:0000313|EMBL:RZC25984.1, ECO:0000313|Proteomes:UP000289340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC   TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZC25984.1};
RA   Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT   "A high-quality reference genome of wild soybean provides a powerful tool
RT   to mine soybean genomes.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RZC25984.1}.
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DR   EMBL; QZWG01000002; RZC25984.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A445LS06; -.
DR   SMR; A0A445LS06; -.
DR   OrthoDB; 5491077at2759; -.
DR   Proteomes; UP000289340; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR   PANTHER; PTHR43574:SF3; UDP-GLUCURONATE 4-EPIMERASE 1; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   PRINTS; PR01713; NUCEPIMERASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000289340};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          93..327
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   431 AA;  47652 MW;  D35CB76BCD41F77C CRC64;
     MPSLEEELFP STPGKFKIER AHHMNRQLYR CFASTSTMFL WALFLIALTA SYLSFQGFVD
     SGSRYLSASW GGIQWEKQVR TSAQIHRQGG MSVLVTGAAG FVGSHVSLAL KRRGDGVVGL
     DNFNDYYDPS LKKARKSLLA KHDVFIVDGD LNDAKLLAKL FDVVAFTHVM HLAAQAGVRY
     AMENPHSYVH SNIAGLVTLL EACKSANPQP AVVWASSSSV YGLNEKVPFS ESDQTDRPAS
     LYAATKKAGE EITHTYNHIY GLSITGLRFF TVYGPWGRPD MAYFSFTRNI LQGKPITVYR
     GKNHVDLARD FTYIDDIVKG CVGSLDTSAK STGSGGKKRG PAPYRIFNLG NTSPVTVPTL
     VSILERHLKV KAKRNIVDMP GNGDVPFTHA NISSARRELG YKPTTDLQTG LKKFVKWYLS
     YYGYNHGKPV N
//