ID A0A445LY94_GLYSO Unreviewed; 1290 AA.
AC A0A445LY94;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=D0Y65_000326 {ECO:0000313|EMBL:RZC28280.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:RZC28280.1, ECO:0000313|Proteomes:UP000289340};
RN [1] {ECO:0000313|EMBL:RZC28280.1, ECO:0000313|Proteomes:UP000289340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZC28280.1};
RA Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT "A high-quality reference genome of wild soybean provides a powerful tool
RT to mine soybean genomes.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZC28280.1}.
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DR EMBL; QZWG01000001; RZC28280.1; -; Genomic_DNA.
DR EMBL; QZWG01000001; RZC28281.1; -; Genomic_DNA.
DR Proteomes; UP000289340; Chromosome 1.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF591; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000289340};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 16..182
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1260..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1290 AA; 146869 MW; 23D0937C1C4449F5 CRC64;
MAGSSSSAAV SLLPVIRHDV FLNFRGEDTR DNFISHIYAE LQRNKIETYI DYRLARGEEI
SPALHKAIEE SMIYVVVFSQ NYASSTWCLD ELTKILNCKK RYGRVVIPVF YKVDPSIVRH
QRETYAEEFV KYKHRFADNI DKVHAWKAAL TEAAEIAGWD SQKTSPEATL VAEIVKDILT
KLNSSSSCDH QEFVGIETHI TQIKLLMKLE TLDIRIIGIW GLGGIGKTTI AGQIYHQLAS
QFCSSSLVLN VPEEIERHGI QRTRSNYEKE LVEGGISISS ERLKRTKVLL FLDDVNDSGQ
LRDLIGGRGR FGQGSRIILT SRDMQVLKNA EADEIYEVKE MNDEESLKLF SIHAFHQNQP
IETYKELSEK VLRYAKGIPL ALQILGSLLY RKTEEVWKNQ LQKLEKYPDS KIFNVLKLSY
DGLDEEQKNI FLDIACFYRG YWEIFVAQQL ESCGFSATIG MDVLKDKCLI SILKGNVQMH
DLIQEMGREI VRQECCLNPG KRSRLWKVEE IHQVLKNNEG TDAVQCILLD TYKINKVKLH
SKTFEKMENL RMLHFFNSHV PWSESNVFLA SSLKSLPDGL KILCWDGFPQ RSLPQNYWPQ
NLVRLEMIRC HLEQLWEPDQ KLPNLKWLDL RYSGKLIRIP DLYLSPDIEG ILLTGCSKFE
IFPEIKDTME NLAVLKLDGT AIKTLPSSLC RLVALEVLSL DSCASLETIP SSIGDLSKLC
KLGLTYCESL ETFPSSIFKL KLTKLDLSRC SKLRTFPEIL EPAQTFAHVN LTGTAIKELP
FSFGNLVHLQ TLRLNMCTNL ESLPNSIFKL KLTKLDLSRC SKLRTFPEIL EPAQTFAHVN
LTGTAIKELP FSFGNLVHLQ TLRLNMCTDL ESLPNSIVKL KLTELDLSGC SKLRTFPEIL
EPAQTFAHVY LTGTAIKELP FSFGNLVQLQ TLHLNLCTDL ESLPNSIVNL NLLSVLDCSG
CAKLTEIPSD IGCLSLLREL SLGESRIVNL PESICNLSSL ELLDLSECKK LECIPRLPAF
LKQLLAFDCQ SITTVMPLSN SLIQIPSNSQ ECNIFRFCFT NGQQLDPGAR ANIMDESRLR
MTEDAYRSVF FCFPGSEVPH WLPFRCEGHS ITIHRDSLDF CRNDRLIGFA LCVVFQLPDT
NDIKRKCGSF SYCLNYVSDH GKHILPNNDN LKSYFYWRDQ ERKLDQDQDH TFLWKYNLEF
PEMSCMSRML PRARSFTFEI SPYYDDNILQ PPSFLSIDRY FKSTVKVKKC GICPLYTKKK
DDNNAGAGDY SGSVRFSKNG IEEPSGSNAA
//
