ID A0A445M3Z0_GLYSO Unreviewed; 1035 AA.
AC A0A445M3Z0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
GN ORFNames=D0Y65_001744 {ECO:0000313|EMBL:RZC30307.1};
OS Glycine soja (Wild soybean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3848 {ECO:0000313|EMBL:RZC30307.1, ECO:0000313|Proteomes:UP000289340};
RN [1] {ECO:0000313|EMBL:RZC30307.1, ECO:0000313|Proteomes:UP000289340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. W05 {ECO:0000313|Proteomes:UP000289340};
RC TISSUE=Hypocotyl of etiolated seedlings {ECO:0000313|EMBL:RZC30307.1};
RA Xie M., Chung C.Y.L., Li M.-W., Wong F.-L., Chan T.-F., Lam H.-M.;
RT "A high-quality reference genome of wild soybean provides a powerful tool
RT to mine soybean genomes.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361199};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZC30307.1}.
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DR EMBL; QZWG01000001; RZC30307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A445M3Z0; -.
DR Proteomes; UP000289340; Chromosome 1.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10810; GH38N_AMII_LAM_like; 1.
DR Gene3D; 2.60.40.1360; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR048534; Man2a1-like_dom.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF61; ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR Pfam; PF21260; Laman-like_dom; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW Hydrolase {ECO:0000256|RuleBase:RU361199};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361199};
KW Reference proteome {ECO:0000313|Proteomes:UP000289340};
KW Signal {ECO:0000256|RuleBase:RU361199};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT CHAIN 27..1035
FT /note="Alpha-mannosidase"
FT /evidence="ECO:0000256|RuleBase:RU361199"
FT /id="PRO_5018812595"
FT DOMAIN 357..431
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1035 AA; 116399 MW; 8BF1C81E1B6920AE CRC64;
MAKKVTIVSH CFSAFLLFYL CGTVVCVKYN TGASVVPGKL NVHLIAHSHD DVGWLKTVDQ
YYVGSNNSIQ GACVENVLDS VVVSLQLNQN RKFVFAEMAF FHRWWVEQTP QTQVQVRKLV
DAGQLEFING GWCMHDEATT HYIDMIDQTT LGHRFIKNQF NKVPRAGWQI DPFGHSAVQA
YLLGAELGFD SVHFARIDYQ DRAKRKVDKT LEVVWRSSKT FGSSAQIFAN AFPVHYSPPS
GFHFEINDDF VPVQDDPLLF DYNVEQRVKD FIAAAITQAN VTRTNHIMWT MGDDFQYQNA
ESWFKQMDKL IHYVNKDGRV NALYSTPSIY TDAKNAANQP WPLKTDDYFP YADGPNAYWT
GYFTSRPAFK RYVRILSGYY LAARQLEFFA GKKSTVGHTI DLGDALGVAQ HHDAVSGTAK
QHTTNDYAKR LAIGASRAEA VVSSSLYCLT SKKLGVQCSA PTSAFSQCQL LNISYCPPTE
DGIPQAKSLV LVVYNPLGWN RSDIVRIPVN DANLVVKDSL GNNIETQYIE VDNVTANLRE
FYVKVYVGVS PQQAPKYWLL FQASVPPLGW STYFISKTAK KGKNRIGFLS YQSSQNKDTI
EVGPGNLKLS FSSESGQLIR MHNSKTGVAV PIQQSYLWYS SSQGEGQVCD FVFYTTLILV
TNKYSTEYVA ISDLLSLQDS GAYIFRPHTP PNIVSRSVPF KIIRGPLVDE VHQEFSSWIY
QVTRVYKDKE HSEIEYTIGP IPIEDGIGKE VITQMTANMV TDKEFYTDSN GRDFLKRVRD
HRDDWPLQVH EPVAGNYYPL NLGIYVKDKK SELSVLVDRA TGGGSIKDGQ VELMLHRRML
FDDGRGVDEG LDELVCQNDR CQGLTVRGNY YVGIHKLGAG SHWRRTTGQE VYSPLLLAFA
HEDLGNWKAF HVTRGTVIDP NYNLPPNVAL ITLEVLDNGM VLLRLAHLYE AGEDAQLSTL
TKVELKKMFA TKMIRGLIEV SLSANQEKEK MKKKTWNVAG DKGQGSKSVR GGPVSHINLV
VELGPMEIRS FLLKF
//
