ID A0A446B849_9PEZI Unreviewed; 1076 AA.
AC A0A446B849;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=A311064f-6696-45c8-853d-d5c5fb1a7b93 {ECO:0000313|EMBL:SPQ18691.1};
GN ORFNames=TT172_LOCUS1110 {ECO:0000313|EMBL:SPQ18691.1};
OS Thermothielavioides terrestris.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Thermothielavioides.
OX NCBI_TaxID=2587410 {ECO:0000313|EMBL:SPQ18691.1, ECO:0000313|Proteomes:UP000289323};
RN [1] {ECO:0000313|EMBL:SPQ18691.1, ECO:0000313|Proteomes:UP000289323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Huttner S., Dainat J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; OUUZ01000001; SPQ18691.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A446B849; -.
DR Proteomes; UP000289323; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 934..950
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 222..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 620..647
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 672..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1076 AA; 117680 MW; BA5E15123493FE6D CRC64;
MLFPRTPPAP RLRIACLGRP ARTLATLRRI GRVGRWGVTT AWAPTRSGGH GPLGIRSPLQ
VRGKKTRTVV KLDELPQGVV APPPELLRPP EEDEPAYPTV VLQARRNMQK FDNCVLLTRV
GGFYEMYFDQ ADEYGPLLNL KAGFPFFQLD RFLKILVQDL NRHVAIAEEF PNDPSEKVKS
GGLMHNRRVT RIVTPGTLID ENFMDPYASN YVMAIHQPEP AAASDDASGL GDRDQRPLGT
PESASIAEAP VGLAWLDLST GSFFTQPTTL ASLGSVLTRV SPREIVLDKA LESGRDHVLL
SVLQEERYLV TYSPPGELRQ LSDWAPLLES EIPAHTVDKF TDSEVQAGNL LLHYVRDRLQ
GLSMKLQPPL RHESMHIMHI DKNSMRSLEI KQTIRDGAFK GSLLHAIRRT VTKSGARLLN
EWLSAPSTSL EVINFRQDLV ARFIDDEELR DAIIVLLRRS HDSQRLVQKF ALNRGDPDDL
LRLANTIKAT EDIVNLLTAS ITAARSGSTP AKDNDCLSTM VGRISLDQPL ELAQHIRDAI
DEEGLVQQHQ IEDSEAGEMM ALAQEIVKTE GTEEDSSLLP KGAASKAATS TKKKNPASIR
DHYGEDSEVW IMKPGASALL TRLHEQLAAL RREKEQLTET LRTRLNAASL TLRWTPTLGH
ICHVKGKDAR QPPTAHNNNN SSGGADQPQQ QQPAAAAAIR TLSSSRTTRS FHQPEWTALG
ESLDKLRFQI RAEEQRVFAG LRARVVRGLV KLRRNARVLD ELDIATSFAR LAAEQGLVRP
TLTAAPQTVI VGGRHPTVEG GLAEQGRTFQ RNDCFLGSAV PALAGEGGGP LGGPGTFGGG
GQAQAQAQAQ THGRVWLITG PNMAGKSTFL RQNALITILA QIGCYVPADY ASLGIVDAIF
SRVGSADNLY QDQSTFMVEM LETAAILRQA TPRSFVIMDE VGRGTTPEDG TAVAFAALHH
LVRVNRCRAL FATHFHDIAD LVAQHGLRVQ DGGPDGAVDM YCTDVEEDEN GGFIYVHKLR
KGVNRQSHAL KVARLAGLPE QAIRVAQQVL QHSGVDISSH RGVEQAKAPA SAAVVA
//
