ID   A0A446BXG9_9PEZI        Unreviewed;       526 AA.
AC   A0A446BXG9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   22-FEB-2023, entry version 12.
DE   RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE            EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE   AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN   ORFNames=TT172_LOCUS9605 {ECO:0000313|EMBL:SPQ27186.1};
OS   Thermothielavioides terrestris.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Thermothielavioides.
OX   NCBI_TaxID=2587410 {ECO:0000313|EMBL:SPQ27186.1, ECO:0000313|Proteomes:UP000289323};
RN   [1] {ECO:0000313|EMBL:SPQ27186.1, ECO:0000313|Proteomes:UP000289323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Huttner S., Dainat J.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001831};
CC   -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC       {ECO:0000256|ARBA:ARBA00009632}.
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DR   EMBL; OUUZ01000019; SPQ27186.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A446BXG9; -.
DR   Proteomes; UP000289323; Unassembled WGS sequence.
DR   GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR   GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR   Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR   Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR   InterPro; IPR026888; AcetylCoA_hyd_C.
DR   InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR   InterPro; IPR046433; ActCoA_hydro.
DR   InterPro; IPR003702; ActCoA_hydro_N.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR   PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR   Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR   Pfam; PF02550; AcetylCoA_hydro; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE   3: Inferred from homology;
FT   DOMAIN          19..233
FT                   /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02550"
FT   DOMAIN          334..484
FT                   /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13336"
SQ   SEQUENCE   526 AA;  58688 MW;  6195B1A1420D45A1 CRC64;
     MASPIASAAL KARIKRPSML KKLCHPEDLL PHFPNGAYIG WSGFTGVGYP KKMPTFLADH
     VEKNNLQGKL RYSLFVGASS GAETENRWAA LDMIERRAPH QVGKNIAKGI NEGRIKFFDK
     HLSMFPVDLV YGFYTRDRPN NRIDVAVVEA TEIKEDGSIV PGASVGATPE LLQLANKIVI
     EVNTALPSFD GLHDITMTDL PPRRKPYLIT DVEDRIGTNS IPIDPEKVIG ILESDYQDQT
     LPNTPADETS QKIAGHLIEF FEHEVKHGRL PASLLPLQSG IGNIANAVIG GLDNSNFRNL
     KVWTEVIQDT FLDLFDSGRL DFATATSVRF SPAGFERFYK NWESYRNKLL LRSQQVSNSP
     EIIRRLGVIG MNTPVEVDIY AHANSTCVLG SRMLNGIGGS ADFLRSAKYS IMHTPSTRPS
     RTDPHGVSCV VPMCTHVDQT EHDLDIIVTE NGLADVRGLS PRERARVIID KCAHELYRPI
     LRAYFEKAES ECLRKGMGHE PHLLWNAFDM HRALQEEGSM QKVKLW
//