ID A0A448IB73_MYCCI Unreviewed; 927 AA.
AC A0A448IB73;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=FAD linked oxidase domain-containing protein {ECO:0000313|EMBL:VEG49694.1};
GN ORFNames=NCTC10485_04006 {ECO:0000313|EMBL:VEG49694.1};
OS Mycolicibacterium chitae (Mycobacterium chitae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1792 {ECO:0000313|EMBL:VEG49694.1, ECO:0000313|Proteomes:UP000282551};
RN [1] {ECO:0000313|EMBL:VEG49694.1, ECO:0000313|Proteomes:UP000282551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10485 {ECO:0000313|EMBL:VEG49694.1,
RC ECO:0000313|Proteomes:UP000282551};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; LR134355; VEG49694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A448IB73; -.
DR Proteomes; UP000282551; Chromosome 1.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR004017; Cys_rich_dom.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02754; CCG; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000282551}.
FT DOMAIN 38..248
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 927 AA; 97495 MW; EDE2212A77784C15 CRC64;
MLRMDPASFV TLLRRAGVSD VLSDGTTRAA YSTDASLYRV PPLVVARPRH VDEIAAALAV
CRAEGVPLTA RGAGTSIAGN AVGTGLVLDF SRHLNRVLAV DPDAAVATVE PGVVQEALQR
HVAPLGLRFG PDPSSSSRCT IGGMIGNNAC GTRALGYGRT SDNVVGLRGI TGAGEALDAA
VVRTGLQRIG EANLAVLRTQ FGRFSRQVSG YGLENLLPER GFDIARLLVG SEGTLAVLTE
ATVALVAEPA HRVLVVLGYP DIAAAGDATP QVLTHRPVAC EGIDSRIVDV VREKHGPQAV
PPLPAGAAWL FVEVTGADLA DTVARAERVG ADCAALAARV VPDRAQAAAL WRIRADGAGL
SSRSPAGLPA HAGWEDAAVP PERLGSYLRD FDALLGEYGL TGLPYGHFGD GCLHIRIDFP
LQKPGGAGVF REFLLAAATL VAGYGGSLSG EHGDGRARSE LLPMMYSLAA MDLFAAVKHV
FDPQNILNPG VVVDPRPFDA DLREPAAPSL RRDLALAYRH DGGDFTQAVH RCTGVGKCRA
DNSATGGVMC PSYRATGEEK DSTRGRARVL QEMINGTVVT DGWRAAEVHE ALDLCLSCKG
CLSDCPTGVD MASLKAEVLH QSYRHRPRPA THYSLGWLPR WARLAATAPR MVNAALRGAG
PRGLALAGVD GRRRIPEFAP QTFRSWFSRR PPSAGDPVLL FVDTFTNYFT PEVGQATVRV
LERAGYAPVL TAKQRCCALT WISTGQLDAA RKILGRTVSE LGATDLPIVG IEPSCTAVLR
SDAAELVGAA ADPVAGRTHT LAELLAARGW EPPDLTGESV LAQPHCHHHA VLGWSPDAAL
LAAAGAQVQR LAGCCGLAGN FGVEKGHYEV SVAVADLELR PAVAAAGPQT TILADGYSCR
TQLADLTDRR GLHLAQLLDR ALTRLAS
//
