ID A0A448KCR2_9ACTO Unreviewed; 656 AA.
AC A0A448KCR2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=maltose alpha-D-glucosyltransferase {ECO:0000256|ARBA:ARBA00012619};
DE EC=5.4.99.16 {ECO:0000256|ARBA:ARBA00012619};
DE AltName: Full=Maltose alpha-D-glucosyltransferase {ECO:0000256|ARBA:ARBA00031378};
GN Name=treS {ECO:0000313|EMBL:VEG74716.1};
GN ORFNames=NCTC11923_01354 {ECO:0000313|EMBL:VEG74716.1};
OS Actinomyces slackii.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=52774 {ECO:0000313|EMBL:VEG74716.1, ECO:0000313|Proteomes:UP000276899};
RN [1] {ECO:0000313|EMBL:VEG74716.1, ECO:0000313|Proteomes:UP000276899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC11923 {ECO:0000313|EMBL:VEG74716.1,
RC ECO:0000313|Proteomes:UP000276899};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-maltose = alpha,alpha-trehalose; Xref=Rhea:RHEA:15145,
CC ChEBI:CHEBI:16551, ChEBI:CHEBI:17306; EC=5.4.99.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001595};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family. TreS
CC subfamily. {ECO:0000256|ARBA:ARBA00005496}.
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DR EMBL; LR134363; VEG74716.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A448KCR2; -.
DR STRING; 1278298.GCA_000428685_02329; -.
DR KEGG; asla:NCTC11923_01354; -.
DR Proteomes; UP000276899; Chromosome 1.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0047471; F:maltose alpha-D-glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11334; AmyAc_TreS; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR032091; Malt_amylase_C.
DR InterPro; IPR045857; O16G_dom_2.
DR InterPro; IPR012810; TreS/a-amylase_N.
DR NCBIfam; TIGR02456; treS_nterm; 1.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF219; MALTOSE ALPHA-D-GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF16657; Malt_amylase_C; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Glycosidase {ECO:0000313|EMBL:VEG74716.1};
KW Hydrolase {ECO:0000313|EMBL:VEG74716.1};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000276899}.
FT DOMAIN 94..489
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 629..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 71863 MW; DAC88C277FDED3A7 CRC64;
MSAAHPAGPE AVAGLAGSPV APAAPSAGPE ALTAPAVATT SGSIPVVRAP LTAGGLPAPM
TITPAIPGVP VLPAQERPGV SADPQWFRTA VFYEALLRSF ADSDGDGVGD LPGLISRLDY
LAWLGVDCLW IPPFYPSPMR DGGYDISDYT AIDPRYGTME DFRELVHQAH QRGIRIVIDM
VLNHTSDAHP WFQSSRSDPE GPYGDFYVWR DDDSGYPGTR IIFVDTEESN WAYDVERGQF
YWHRFFSHQP DLNYDNPAVI EAVHDVVRFW ARTGVDGFRL DAIPYLVEVE GTNCENLGGT
HEVIAGIRAM LDREFPGVIT IAEANQWPHD VVEYFGTDEA PECTMCFHFP VMPRIYYALR
AESATAIRWV LERTPQIPAH GQWGTFLRNH DELTLEMVTD AEREQMYAWY APEERMRANV
GIRRRLAPLL DASRAEIELA HALLMSLPGS PCLYYGDEIG MGENIWLEDR DAVRTPMQWD
DSPNMGFSTA VDPGALTLPV IQAPGYAHLT VATEMGRPDS LLHFTRRLLH LRRAHPVLGR
GDFRLRDTSD EAVLAHTRSD DPETADGETL LCVANLSAVP RSVRIEVPEL AGMSTLDVFG
GTAFPDIDDS GLLTLTLGAR GYYWLAVAPG PDASPAPEGE DAGSTGAPAQ DDQEGA
//
