ID A0A448VLH6_9NEIS Unreviewed; 597 AA.
AC A0A448VLH6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Aminopeptidase {ECO:0000313|EMBL:VEJ50649.1};
DE EC=3.4.-.- {ECO:0000313|EMBL:VEJ50649.1};
GN ORFNames=NCTC12742_00803 {ECO:0000313|EMBL:VEJ50649.1};
OS Neisseria weaveri.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=28091 {ECO:0000313|EMBL:VEJ50649.1, ECO:0000313|Proteomes:UP000272771};
RN [1] {ECO:0000313|EMBL:VEJ50649.1, ECO:0000313|Proteomes:UP000272771}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12742 {ECO:0000313|EMBL:VEJ50649.1,
RC ECO:0000313|Proteomes:UP000272771};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LR134533; VEJ50649.1; -; Genomic_DNA.
DR RefSeq; WP_004282599.1; NZ_POXF01000001.1.
DR AlphaFoldDB; A0A448VLH6; -.
DR STRING; 28091.SAMEA3174300_01428; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000272771; Chromosome 1.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:VEJ50649.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:VEJ50649.1};
KW Protease {ECO:0000313|EMBL:VEJ50649.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000272771}.
FT DOMAIN 7..129
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 313..522
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 537..597
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
FT COILED 228..255
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 597 AA; 65845 MW; AE74C090D5FEA49F CRC64;
MSTVVERIRT LRETMQQHRI DAWIIPTADP HLSEYLPEHW QSRVYFSGFT GSAGTLVVTA
KQAGLWADSR YWEQAAQQLS GSGITLQKLG AVPNYTEWLS QHLPEQAVVG IAPDMLSLNA
KQQLLSAFTD RHILLQHDQD IAANVWPQRP TLPSSTIFVH NPEYVAESAA AKLNRIRSFM
HQQGVAHHLV SSLDDIAWIT NLRGSDVSYN PVFLSFLLIS HNRATLFLVD QQQLNEEARQ
LLAEAQIDTA DYQDAAAALA QLSGGLMIDP ARTAVSTLQY LPKDLKTVEH INPSTLFKSI
KSSADLAYIR TTMAQDGAAL CGFFAEFERK IAAGEAVTEL DVDTMLLAHR SRRNGFVSPS
FGTIAGFNQN GALPHYSATP EAHSIITGNG LLLIDSGGQY HGGTTDITRV IPIGTPSEEQ
KRDFTLVLKA HIALATTIFP ENIPGPMLDA ICRKPLWQAQ CNYGHGTGHG VGYFLNVHEG
PQTIAYMAPV NPNHAMKAGM ITSNEPGLYR PGKWGIRIEN LVANVPVDSP AETEFGNYLR
FETLTLCPID TRLIEKTLLT AEETDWLNSY HAEVREKLLP LVEGEAKAWL EAQTQSI
//
