ID   A0A448YIN9_BRENA        Unreviewed;       706 AA.
AC   A0A448YIN9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=DEKNAAC101625 {ECO:0000313|EMBL:VEU20751.1};
GN   ORFNames=BRENAR_LOCUS1486 {ECO:0000313|EMBL:VEU20751.1};
OS   Brettanomyces naardenensis (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Brettanomyces.
OX   NCBI_TaxID=13370 {ECO:0000313|EMBL:VEU20751.1, ECO:0000313|Proteomes:UP000290900};
RN   [1] {ECO:0000313|EMBL:VEU20751.1, ECO:0000313|Proteomes:UP000290900}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tiukova I., Dainat J.;
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC       {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004128}.
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DR   EMBL; CAACVR010000006; VEU20751.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A448YIN9; -.
DR   STRING; 13370.A0A448YIN9; -.
DR   InParanoid; A0A448YIN9; -.
DR   Proteomes; UP000290900; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033254; C:vacuolar transporter chaperone complex; IEA:UniProt.
DR   GO; GO:0006799; P:polyphosphate biosynthetic process; IEA:UniProt.
DR   CDD; cd07751; PolyPPase_VTC4_like; 1.
DR   CDD; cd14480; SPX_VTC2_like; 1.
DR   Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018966; VTC_domain.
DR   InterPro; IPR042267; VTC_sf.
DR   PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR   PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR   Pfam; PF02656; DUF202; 1.
DR   Pfam; PF09359; VTC; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290900};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT   TRANSMEM        643..666
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        687..705
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..152
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   COILED          89..116
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   706 AA;  81936 MW;  3D4ABF6DEC1FB12F CRC64;
     MKFGETLKSS LLKEFTYYYI QYDELKHFIK HGLDETNKKW SGQLEEEFVN RLEEELSKIF
     DFTTLKEEEI NRRIADVEKL VNKTVENSRN ANAEEMEYYE QDYEDLEDEL RDIISSVYDL
     NTFTQLNYTG FQKILKKHDK QTKYILKPIY QSRLDAKPFY KTNTDEMIVK LSKLYDLVRT
     RGDPAKGDSA AGGTTQNFVR QTTKYWVHPD NITELKLIIL QHLPVLVFNP NKDWEADDSA
     ITSIYFDNEN MDLYYGRLLK TEGAEAIRIR WYGNMDVDGM FIERKTHRED WTGEKSVKAR
     FPIKESKIND FLKGKFTAKQ AFEKMRKEGR KSTEEIDSLE RLAQEAQYRI IKDGMRPVMR
     TFYHRTAFQL PGDARVRISL DTELTMVRED NFDGIDRTKG NWRRMDIGIN YPFSNLPAAD
     VERFPYAVLE VKLQTQLGQE PPQWVKDMVS SHLVEAVPKF SKFIHGCSTL LPQKVDLIPF
     WLPQMDVDIR KPKFDESYGI VHAQENGQAA GSAPGNNLDE EELVASNGSH NYGAVRIDES
     NNRIEQLPDQ PETTWDKILD KVKDFYKYTF HSGNEEFENT VAPGTVYDTE VRAPPGKKIA
     VPVRVEPKVY FATERTYLSW LTISLIFAGT GQALMSYGDI VSFMTSTCFY LLSALTILYS
     TGMYVWRVTN VRKKRAARYD DQIGPDAVCG AMVIAVLVNF VFRYVY
//