ID A0A448YNQ1_BRENA Unreviewed; 1175 AA.
AC A0A448YNQ1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=DEKNAAC103637 {ECO:0000313|EMBL:VEU22574.1};
GN ORFNames=BRENAR_LOCUS3305 {ECO:0000313|EMBL:VEU22574.1};
OS Brettanomyces naardenensis (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=13370 {ECO:0000313|EMBL:VEU22574.1, ECO:0000313|Proteomes:UP000290900};
RN [1] {ECO:0000313|EMBL:VEU22574.1, ECO:0000313|Proteomes:UP000290900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tiukova I., Dainat J.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
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DR EMBL; CAACVR010000023; VEU22574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A448YNQ1; -.
DR STRING; 13370.A0A448YNQ1; -.
DR InParanoid; A0A448YNQ1; -.
DR Proteomes; UP000290900; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR032632; Peptidase_M16_M.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF16187; Peptidase_M16_M; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000290900};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 32..157
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 545..764
FT /note="Peptidase M16 middle/third"
FT /evidence="ECO:0000259|Pfam:PF16187"
SQ SEQUENCE 1175 AA; 131256 MW; E1C3345FA9A6EBF5 CRC64;
MSYTFPNRFP VPCSAKGRSY KFIKLENGIR CLIISDPTED VASMSLSVAT GHHADPSAVP
GLAHLCEHMV CVSSKEYPQV DLYKTMVHEV GGSWNAVTVN EKTSFFFRIP LIASSDDLDQ
ESSFSKIIKV FASYFKHPLF DSNYADREVV AVDNENAKNC SLTSRISFHG LRLLANPNCQ
FHRFSTGNYE TLHGISSTVS IKATLKAFFK AEYLPERMAV VLKGPQTLNY LQRVATSAFS
SIGDQKKTGL SLFRKHTEIT SPHPREDLLQ SQVAADVWLR RYKTVTFPSR GGRFILIHKK
GSGDTILRLF FPINLQSISF SAKQLEIFQS FWCHILGSES FGSLNSKYIS SQYVTELIAK
VATISSSTNA LELQLALSRE GARNLDKVIR LFFDFTSLFS GDDPKFKRKL AKAFSQFNGI
ELYNFYYAEA GAGGTDEIRA FSERLLSPLE VFGQWFFRGS PCFDSTDKGF AGSFHESESF
WIREANKFIS FVNDIVSPDN LLFSYVGDTE LVGESLGSEN LPSFKDANFK FSYKMGRLAM
SSHSGCSTAF SIPPPNAFAP SITDEQCNLL DMFKAIEESS LEAGLGYSVK NISAISLPQL
AFSDDGTQFW IKKESDPIYM DKLFLSVELT SLVDRGKTTC SHVIVLELLC DLVKVKLRET
LYPALVMGYS YDIFPSLKGD TGIVIHIAGP KSRILNVFSL IVYEAKAVSS DFKINVTPTE
FRNSRIRIQK KYSAGQSLPS HSLVSLGLMA VMEENTWLLD TRMEALEDLN FATADSICSH
LFDVCYSTFL IHGDVDDIMA SRYGVLDCLN SLVKEFKGQN DCFVPSTIHL PQNCNYIAKD
TCKDPTNALA YFLQTSPRSD TPSRAITRLL AFILSNSLLS KLRIQYQLGY VVLVGSRVFR
KVEGIHITIM SGQMGPEALE AKVEEIIMEW YEEFVKDLDE TKFKSLYVNK FLAAYSSINQ
KMNTAGRAPS LTQGSLISGM SGSALAKQHQ GYWDQIVNRS YRFSQNLTGE DTIDVSVIEQ
LRLDDFLSFI KARILPNSGS RIKVSAMLTT ERSREDVEQM LTPVRIYFFL SSVGLPIKKD
ALVDILKTSG DSKIALCKNL LKYYRSQGKA LRLISAGLAK MSLAVLPGPG NLSVDFHRHS
EPVHIDPVHL QEWQRGIGFI HGESLSVTLS RFSGR
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