ID A0A448YR29_BRENA Unreviewed; 954 AA.
AC A0A448YR29;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=DEKNAAC104674 {ECO:0000313|EMBL:VEU23399.1};
GN ORFNames=BRENAR_LOCUS4130 {ECO:0000313|EMBL:VEU23399.1};
OS Brettanomyces naardenensis (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=13370 {ECO:0000313|EMBL:VEU23399.1, ECO:0000313|Proteomes:UP000290900};
RN [1] {ECO:0000313|EMBL:VEU23399.1, ECO:0000313|Proteomes:UP000290900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tiukova I., Dainat J.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; CAACVR010000045; VEU23399.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A448YR29; -.
DR STRING; 13370.A0A448YR29; -.
DR InParanoid; A0A448YR29; -.
DR Proteomes; UP000290900; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000290900}.
FT DOMAIN 826..842
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 34..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 954 AA; 107893 MW; 7B1273275DC814E4 CRC64;
MSWRYLAKVR EASKVNLSDI EIVTAKVDQL DSLKEQVERP RMRMTKSDKH GRSSKAGKSD
RSNRANGSAQ GAQKAAPIVD RGAITADNSL TDFYQEMKAI IDKYSHRIDG EYVVLVQVGS
FYELYFEQAE RHANMLGLTL TKKKLKNQDV SFAGFPDYKL DKYLKIIFTE GLKAVICDQK
RNGFDNVIKR PIDRLVTPGT VVDDGLRDYH RNNFLLAITF PDDPFKTEIP DGKIGLAWCD
VTLGSFHVLE TNFNDLMAAI TRINPSEIVV NNSFKIDYLA SGRWLPQFAD LRRYYITKFS
IPSTKKHIEE FTGRFSENKR LIISTFDDLK MKELSASKLL LYYLDECIPN YVTSFQLPAR
SFPNEVMHID PRAAQDLELT ETIRGGLRVG ALANIIDRTQ TNPGARLLNS WLLMPSTDIS
EIKKRQKVVS IMLRYEDFTE DLVVLLRKTS DTSRIIRRVD NNRAELSEYL ELSSTVFLLE
EIYKIASETP QILKVISPLF EKFNSTPQIH KLALLIKRTV DPNAPSKAES IGFNGFRLDT
DITRHSWRIQ RLASKRLSEL RNTYDTYLEE YDALHALMKT KLEVFGYTGG LRLIRHLRTG
EFLVELKSSS KSLSTVVDEI SMKHKEKTKT SVKLVVPEWE ELGRKLIHLE SDILLEESLI
MRDLERKIFS LANSLKDISP IIEFLDTTQS FANLAREKNL VCPEVDSSTD FEIAEGRHLV
VEEGLKDRSL GVENFTSNSC SLKSGRAWII TGPNMGGKST FLRQNALIAI LAQIGSFVPA
VSARIGIIDK IFTRVGSSDS IFKNQSTFMV EMNETAIILR ESTEKSLVIV DELGRGTSTG
EGVAIAFASL LTMVKTNSSK VLFATHFGPE LFDKIQSCPE LDDCIEFYRS ELKKIDSNVL
PIDEKIVFNH KLKRGLSVHS HALEIAELAG FPASTLRIAV HSLGRSGERE ITVE
//
