ID   A0A448ZS51_9STRA        Unreviewed;      1236 AA.
AC   A0A448ZS51;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   RecName: Full=Cathepsin propeptide inhibitor domain-containing protein {ECO:0000259|SMART:SM00848};
GN   ORFNames=PSNMU_V1.4_AUG-EV-PASAV3_0120210
GN   {ECO:0000313|EMBL:VEU44880.1};
OS   Pseudo-nitzschia multistriata.
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC   Pseudo-nitzschia.
OX   NCBI_TaxID=183589 {ECO:0000313|EMBL:VEU44880.1, ECO:0000313|Proteomes:UP000291116};
RN   [1] {ECO:0000313|EMBL:VEU44880.1, ECO:0000313|Proteomes:UP000291116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B856 {ECO:0000313|EMBL:VEU44880.1,
RC   ECO:0000313|Proteomes:UP000291116};
RA   Ferrante I. M.;
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CAACVS010000674; VEU44880.1; -; Genomic_DNA.
DR   Proteomes; UP000291116; Unassembled WGS sequence.
DR   Gene3D; 1.10.287.2250; -; 3.
DR   InterPro; IPR013201; Prot_inhib_I29.
DR   PANTHER; PTHR10013; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   PANTHER; PTHR10013:SF0; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   Pfam; PF08246; Inhibitor_I29; 2.
DR   SMART; SM00848; Inhibitor_I29; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291116};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..1236
FT                   /note="Cathepsin propeptide inhibitor domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019320920"
FT   DOMAIN          92..154
FT                   /note="Cathepsin propeptide inhibitor"
FT                   /evidence="ECO:0000259|SMART:SM00848"
FT   DOMAIN          205..255
FT                   /note="Cathepsin propeptide inhibitor"
FT                   /evidence="ECO:0000259|SMART:SM00848"
FT   DOMAIN          305..355
FT                   /note="Cathepsin propeptide inhibitor"
FT                   /evidence="ECO:0000259|SMART:SM00848"
FT   REGION          133..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          501..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          796..914
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          603..657
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        154..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        796..844
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        845..879
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        897..911
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   UNSURE          984
FT                   /note="D or N"
FT                   /evidence="ECO:0000313|EMBL:VEU44880.1"
SQ   SEQUENCE   1236 AA;  140582 MW;  886117C2983226B0 CRC64;
     MRLPTFVALI LFVARITERE DSSIFAYYVP GTPCRLSXRE RSCLPWSRNT DYRNDDXLVT
     TSLKFSAVDT TAGLEDXNIY FSGDEERILX VYDQWRNEYG KGDFDGTRYQ NFRSNYIKLM
     TANAAELTVA RDMGYPDPEP LSLNEYGDYS PEEFHSMQNG QYAAPTSSDS AVPASLNGYG
     SPQTRSPYGE NYYSAEEQDR IRQIYKEWCY XNGKNYDESR LEIFANNLRV VENYFKQTGK
     KAELNQYADV SPEEYKEIXT LESQNTQSQY NAPHVETMST NRHTSPSTLY NFYDENEVER
     IXQAYMAWCS DYGKDYDESR LDIFAVNLFA IENYRTETGK NVNLNAYADL SPDEFNSIRS
     SGAEIPFDGG NSYAGTLPNN GSEYYGELNG VSSGTNYGSG SLSEENPLAT TDEGIXTMYT
     KWCXYYGKVP SDDGFYYFKT KYAILEKGYL ETGVEFTMNE YADLPEQTET QQPGTLGVEG
     ERMHTEDARL AEEEERRAEA AKLEKEQNER LELAQQQRAQ EMIQAEEERK RREEEARLQN
     EKMEREKFEE ARRRVEEARL LEQKRNTAAA KASLEEIEAA AEKVIAEESA LIXNDSNLXQ
     LXSERNRLQQ ERERIEEALK VDRARLNEEK RREELARIAL EDTNRKLQEK LKENEEDSVD
     EPDPIIVPRA SYLDAVAKTW VDRTAYLEAL QEGRVGVLPG ELNLPQKPIP KXTQEEKETR
     IKRSESLIDS IWNFMKEDGS DEASTQSTGV MGEELRYLKK AVDAMRRRNN DDRAAERAIV
     EAKDWEQIQK GLEKEAKRAK KRREHEERLA GEAREKARSL KSEKREHDKH AEEARKEERA
     LQKQNGXSTE DNKDIFSFFS SPFQANESTN GSKEENMFSF FSAGKSDVRK NAPPANKPAM
     NTPPKNPPPP NSMTQAVKVK KXEDSWINAV FGFFAGEKEE ETTPGLGTIT LEPAPRKSVF
     DLFVSPDEIA PAREAGRGSI TIDDSKEPSI FSFFARFGIS QKKEKEVDPV RLKRLMDYEK
     KVRVREEKLS RLRAGRSRIL EEKDRKMSRK EARKLQRELD ALAAGNFTSS ARNTNIPQLA
     KWTSTPEGRI TGFISDSAGG PYKLGSKITT SPIKGKIAKP GITVTTITGS KYRLGMIAPR
     DAIDSASGSR ETASKRSSDQ ISPMGSFFGR LFPEENIPCL VEWTQNEDGT ITGFINNKEG
     FEDGTQITTS PVQKGARRGM VIQTRGGSKY KLMKPQ
//