ID A0A452C5I3_BALAS Unreviewed; 605 AA.
AC A0A452C5I3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Apoptosis-inducing factor 3 isoform X5 {ECO:0000313|RefSeq:XP_028018195.1};
GN Name=LOC103020028 {ECO:0000313|RefSeq:XP_028018195.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028018195.1};
RN [1] {ECO:0000313|RefSeq:XP_028018195.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028018195.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00006442}.
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DR RefSeq; XP_007196345.1; XM_007196283.1.
DR RefSeq; XP_028018195.1; XM_028162394.1.
DR AlphaFoldDB; A0A452C5I3; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd03478; Rieske_AIFL_N; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR028202; Reductase_C.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR PANTHER; PTHR43557:SF8; APOPTOSIS-INDUCING FACTOR 3; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF14759; Reductase_C; 1.
DR Pfam; PF00355; Rieske; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 70..165
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
FT REGION 22..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 66585 MW; 0D4575A9C3059A62 CRC64;
MGGCFSKPKP VELKIEVVLP EKDRGKEELS TGGKGSPRAY QGQGTACHFH AEERLPAPHP
YPGAQDCVEA AVCHIKDLEN GQMREVELGW GKVLLVKDNG EFHALGHKCP HYGAPLVKGV
LSRGRVRCPW HGACFNISTG DLEDFPGLDS LHKFQVKIEK EKVYVRASKQ ALQLQRRTKV
MATCISPSTG HSSSTNVLIV GTGAAGLVCA ETLRQEGFSD RIVLCTLDRH LPYDRPKLSK
SLDAQPEQLA LRPKEFFRAH GIEVLTEAQV VTVDVRNKKA VFKDGFKLEY SKLLLAPGSS
PKTLSCKGKD VENVFTIRTP EDANRVVRLA RGRNAVVVGA GFLGMEVAAY LTEKAHSVSV
VELEETPFRR FLGERVGRAL MKMFESNRVK FYMQTEVSEL RAQEGKLKEV VLKSSKVLRA
DVCVVGIGAV PATGFLRQSG IGLDSRGFIP VNKMMQTNVP GVFAAGDAVT FPLAWRNNRK
VNIPHWQMAH AQGRVAAQNM LAQEAEISTV PYLWTAMFSK SLRYAGYGEG FDDVIIQGDL
DELKFVAFYT KGDEVISVAS MNYDPIVSKV AEVLASGRTI RKREVELFVL HSKTGDMSWL
TGKGS
//
