ID A0A452C5Y2_BALAS Unreviewed; 2065 AA.
AC A0A452C5Y2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Fer-1-like protein 5 {ECO:0000313|RefSeq:XP_028018452.1};
GN Name=FER1L5 {ECO:0000313|RefSeq:XP_028018452.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028018452.1};
RN [1] {ECO:0000313|RefSeq:XP_028018452.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028018452.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ferlin family.
CC {ECO:0000256|ARBA:ARBA00007561}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_028018452.1; XM_028162651.1.
DR STRING; 310752.A0A452C5Y2; -.
DR InParanoid; A0A452C5Y2; -.
DR OrthoDB; 991411at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04011; C2B_Ferlin; 1.
DR CDD; cd04017; C2D_Ferlin; 1.
DR CDD; cd04037; C2E_Ferlin; 1.
DR CDD; cd08374; C2F_Ferlin; 1.
DR Gene3D; 2.60.40.150; C2 domain; 6.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037720; C2B_Ferlin.
DR InterPro; IPR037723; C2D_Ferlin.
DR InterPro; IPR037724; C2E_Ferlin.
DR InterPro; IPR037725; C2F_Ferlin.
DR InterPro; IPR012968; FerIin_dom.
DR InterPro; IPR037721; Ferlin.
DR InterPro; IPR012560; Ferlin_A-domain.
DR InterPro; IPR012561; Ferlin_B-domain.
DR InterPro; IPR032362; Ferlin_C.
DR InterPro; IPR006614; Peroxin/Ferlin.
DR PANTHER; PTHR12546; FER-1-LIKE; 1.
DR PANTHER; PTHR12546:SF34; FER-1-LIKE PROTEIN 5; 1.
DR Pfam; PF00168; C2; 7.
DR Pfam; PF08165; FerA; 1.
DR Pfam; PF08150; FerB; 1.
DR Pfam; PF08151; FerI; 1.
DR Pfam; PF16165; Ferlin_C; 1.
DR SMART; SM00239; C2; 6.
DR SMART; SM00694; DysFC; 2.
DR SMART; SM00693; DysFN; 2.
DR SMART; SM01200; FerA; 1.
DR SMART; SM01201; FerB; 1.
DR SMART; SM01202; FerI; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 7.
DR PROSITE; PS50004; C2; 7.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1969..1987
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..99
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 152..265
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 308..425
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1053..1190
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1234..1353
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1474..1594
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1712..1860
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 2065 AA; 239045 MW; 95358E836E6BF20D CRC64;
MLQLVVWSAN ISPPLSPPPR PCVSVYFRDV KRTTREVEGN HPIWNETLIW HLWNSPLQKD
SFLQITLRDM GSIKKERFIG LATILLKPLV NKPSKILFMK DLTLLNHSMM PTDCTLTLQV
ALMTYKDIEK IGGEDHLAIM AQEVARQKRT FPSSAVHKAL SPKPQHFQVR VKVFEARQLM
GNDIKPVVKV VIGGYQHHTR IKMGNNPFFN EIFFQNFYEV PAKFFDETIL IQVMNSSVMR
FNAEIGRFQT DIGFIYNSPG HTLLRKWLGL CQPNEPSSGV RGYLKVTISA LGVGDQAPVD
QKLTYRADDT DIQIFKSSVV PINMAYLQFF IYCAEDLHLK KHHSVSPMLE VELIGEKLKT
HVQMQTESPI WNQILTFRTQ LPCLSSYIKF RVLDCPRNKC HDEIGTVSLS LNQISSTGAE
IEGMYSGFLP CFGPSFLTLR GGKKAPFRIK EEDATIPNIV KDGLAYRGRV FLELITHIKS
HQDAKMKDLS RDVISVEKHQ NRQKYGLCVI FLSCTMMPNF KDLIQFEVSI GHYGNKMDLS
YKPLVSTTQY SQVIYDGNIY HYVPWYNTKP VVAVTSYWED VSFRMNCLNL LQFTRDRLKA
NLDTLKSMRN PRDPALLPQW EKLLRELMED CKRPLPCMAD QPKATNLDMK RWQLRRLLLQ
QLAQKAKEAQ PRDMVATAEG WLYRLNAVLP EPQMNLPDVM IWLMSREQRV AYAQVPAHTI
LFSPTGARHS GRFCGKTQTL FLQYPEGEGK KDTLPAQLRV CMWLGNVTDS KDLQLLRQGE
VVVSAETYEN QAKYKDQWGQ QWLQHCPSFS DVMGHKALPR EDFKEPHGWH WQGPWTAEPQ
RRLLLDTDIN KSQVLEEVYE NQHRDATGAW VPAAIPNTDA NGEPVEAREN VKCPQGWHVK
KNWAVELNHA VDKEGWEYGV GIPPSGLPQV WNSVEKTYYS CRRRRWARVR YRDHGRLSHE
QETLSFLQLV RGCLDEEGWE YGVFGSKFHL KPQPQSRFRR RRWHRRLAPN KVKGIAPIFL
LEGSLSLDMK QQAKREADMV SSTRRLDRIR SSWRAPPEIT QPPNLPFIYC VFNKPHYYQL
FCYIYQARNL MSNHIQTFQA PFIRLVFLNH SQCTQTLKSS AAPTWAQTLI FQHLLLYENP
QDTKESPPFV VLELWQRDTQ GNESLWGRSM WSPAVWLDVQ NRILPPMRWH PLVKGLEEEE
GEILASCELI LETEVLGERA RPGAQHLPIL SVPWKNGIYI LPKSIQPTLR KMAIEMLVWG
LRNMKQVRSP RLLVECWEES VQTEPIRDFQ TNPNFTQSAL FLTLYMPTDE AFALPLVLKV
VDHQDFGQET VVGQANVDSL QPYFCDPWAE DYMPPRPPML SVKKYQELLG YLYEKFWFKS
SQAEDEHEQE VDWWSKLLWA TGDAPQSLKY KYKEYHALKV YDCELEAVPA FQGLQDFCQT
FKLYQERPKL DSPVVGEFKG QFRVYPFPEN PEAPKPPRQF LPWPKKEDFP QQCLVRVYVV
RAVNLQPQDT NGLCDPYVIL KLGETKLGNR DKYQPNTLDP IFGVMFEMSC TIPLKKDLEI
QLYDFDLFSP DDKIGTTVID LENRLLSGFG ARCGLSKSYC QSGPFRWRDQ MPPSLLLEHH
AKQKGLPPPL FSPEDDSVFY NGKKFRLQSF ELKPPTARFL GPKKERLALY LLHTQGLVPE
HVETRTLYSD SQPGIDQGKV QMWVDIFPKK LGPPGPPFNI RPRKPRRYEL RCIIWKTAHV
DLKENSLSTE KMSDIYVKGW LFGLEKDMQK TDVHYHSLTG EGIFNWRFIF TLDYLAAEQA
CVLSQKDYIW SLDPTLMKFP ARLIIQIWDN NIISADDFLG VLELDLTDMP LPARHAKLCS
IRMMDADPKW PHFLQYKHCS LFKMKNVSGW WPCQVLDGGK WRLSGKVKMT LEILTEKEAL
IKAAGRGQSE PNQYPTLHPP LRTHTLLMWF RSPIARFIHV FWKRYRFKII AISIILLIGL
LLFNFIYSAP NYLAMSWVKP ELRLNAPIQI YTNIINSLNT SNTNSSNLTT PHQNLKSTTG
HKLKLLQGHI NHLQAIFPEL PAPPD
//
