ID A0A452C720_BALAS Unreviewed; 415 AA.
AC A0A452C720;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Homeobox protein Meis3 isoform X1 {ECO:0000313|RefSeq:XP_028018903.1};
GN Name=MEIS3 {ECO:0000313|RefSeq:XP_028018903.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028018903.1};
RN [1] {ECO:0000313|RefSeq:XP_028018903.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028018903.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC {ECO:0000256|ARBA:ARBA00009661}.
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DR RefSeq; XP_028018903.1; XM_028163102.1.
DR AlphaFoldDB; A0A452C720; -.
DR STRING; 310752.A0A452C720; -.
DR InParanoid; A0A452C720; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR032453; PKNOX/Meis_N.
DR PANTHER; PTHR11850:SF190; HOMEOBOX PROTEIN MEIS3-RELATED; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16493; Meis_PKNOX_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000313|RefSeq:XP_028018903.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 299..362
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 301..363
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 64..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..86
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45119 MW; 2C763ACB4FCDC555 CRC64;
MARRSSRGLG VGTVLGEVGL TRQGQGILFR CPGDGETGEE YDELPHYPGI VDSTAALAGF
SEAVPSAPRA PGPYGPHRPP QPPPLGLDSD GLRREKDEIY GHPLFPLLAL VFEKCELATC
SPRDGAGTGL GTPPGSDVCS SDSFNEDIAA FAKQVRSERP LFSSNPELDN LMIQAIQVLR
FHLLELEKVH DLCDNFCHRY ITCLKGKMPI DLVIEDRDGG CREDLDDYPA SCPSLPDQNT
TWIRDHEDSG SVHLGTSGPS SGGLASQSGD NSSDQGDGLD TNVASPSSGG EDEELDQEPR
QNKKRGIFPK VATNIMRAWL FQHLSHPYPS EEQKKQLSQD TGLTILQVNN WFINARRRIV
QPMIDQSNRT AGQGAAFSPE GQPMAGYTET QPQVTVRPPG SMGMSLNLEG EWHYL
//
