ID   A0A452CDU3_BALAS        Unreviewed;       754 AA.
AC   A0A452CDU3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|RefSeq:XP_028021160.1, ECO:0000313|RefSeq:XP_028021169.1};
DE   SubName: Full=Alpha-N-acetylglucosaminidase isoform X2 {ECO:0000313|RefSeq:XP_028021161.1};
GN   Name=LOC103011932 {ECO:0000313|RefSeq:XP_028021169.1};
GN   Synonyms=LOC103008440 {ECO:0000313|RefSeq:XP_028021160.1,
GN   ECO:0000313|RefSeq:XP_028021161.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028021169.1};
RN   [1] {ECO:0000313|RefSeq:XP_028021160.1, ECO:0000313|RefSeq:XP_028021161.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028021160.1,
RC   ECO:0000313|RefSeq:XP_028021161.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome {ECO:0000256|ARBA:ARBA00004371}.
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DR   RefSeq; XP_028021160.1; XM_028165359.1.
DR   RefSeq; XP_028021161.1; XM_028165360.1.
DR   RefSeq; XP_028021169.1; XM_028165368.1.
DR   STRING; 310752.A0A452CDU3; -.
DR   InParanoid; A0A452CDU3; -.
DR   OrthoDB; 1112009at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024732; NAGLU_C.
DR   InterPro; IPR024240; NAGLU_N.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   Pfam; PF05089; NAGLU; 1.
DR   Pfam; PF12972; NAGLU_C; 1.
DR   Pfam; PF12971; NAGLU_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..754
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5036634420"
FT   DOMAIN          100..127
FT                   /note="Alpha-N-acetylglucosaminidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12971"
FT   DOMAIN          141..476
FT                   /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF05089"
FT   DOMAIN          485..743
FT                   /note="Alpha-N-acetylglucosaminidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12972"
SQ   SEQUENCE   754 AA;  83819 MW;  75EE958F9DAF8900 CRC64;
     MEAVAVAAGL GFLLLTAAGG SAGDEAREAA AVKELLARLL GPGPAAAFSV SVERALAAES
     GLDTYRLSGG GXXXXXXXXX XXXXXXXXXX XXXXXXXXXL HRYLRDFCGC HVAWSGSQLR
     LPQPLPAVPE ELTEATPNRY RYYQNVCTQS YSFVWWDWAR WEQEIDWMAL NGINLALAWS
     GQEAIWQRVY LALGLTQTEI DEYFTGPAFL AWGRMGNLHT WSGPLPPSWH LKQLYLQHRI
     LDRMRSFGMI PVLPAFAGHV PKALTRVFPQ INITQMGSWG HFNCSYSCSF LLAPEDPLFP
     IVGSLFLREL TKEFGTDHIY GADTFNEMQP PSSEPSYLAA ATATVYQAMI AVDPDAIWLL
     QGWLFQHQPE FWGPAQVGAV LGAVPRGRLL VLDLFAESQP VYVRTASFQG QPFIWCMLHN
     FGGNHGLFGA LESVNRGPTA ARLFPNSTMV GTGMAPEGIG QNEVVYALMA ELGWRKDPVA
     DLGAWVTGFA ARRYGVSHGA AEAAWRLLLR SVYNCSGEGC SGHNRSPLVR RPSLQMATAV
     WYNRSDVLEA WRLLLAATPT LATSPAFCHD LVDVTRQAVQ ELVSLYYEEA RTAYLNKELV
     PLMRAGGVLA YELLPALDKV LASDSHFLLG SWLERARVAA VSETEARFYE QNSRCQLTLW
     GPEGNILDYA NKQLAGLVAD YYAPRWRLFM ETLVESLVRG IPFQQHQFDK NAFQLEQTFV
     LSTRRYPSQP QGDTVDLAKK LFLKYYPRWV AGAL
//