ID   A0A452CLL1_BALAS        Unreviewed;       518 AA.
AC   A0A452CLL1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Septin-8 {ECO:0000256|ARBA:ARBA00023867};
GN   Name=SEPT8 {ECO:0000313|RefSeq:XP_028023896.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028023896.1};
RN   [1] {ECO:0000313|RefSeq:XP_028023896.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028023896.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC       vesicle membrane {ECO:0000256|ARBA:ARBA00004432}. Presynapse
CC       {ECO:0000256|ARBA:ARBA00034106}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Septin GTPase family.
CC       {ECO:0000256|RuleBase:RU004560}.
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DR   RefSeq; XP_028023896.1; XM_028168095.1.
DR   AlphaFoldDB; A0A452CLL1; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01850; CDC_Septin; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016491; Septin.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF54; SEPTIN-8; 1.
DR   Pfam; PF00735; Septin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT   DOMAIN          117..383
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   REGION          452..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  59897 MW;  7CE2BEBAFD3CF327 CRC64;
     MGTAGEDEAL GILGVPQMSP GQLQTWVLKT TAFFFPLHSP PPPPKLPDPG CDSRQVWPQW
     SGLKQPFPRN WRDSRFSPVD VWAPIQNAEP EPRSLSLGGH VGFDSLPDQL VSKSVTQGFS
     FNILCVGETG IGKSTLMNTL FNTTFETEEA SHHEECVRLR PQTYDLQESN VQLKLTIVDA
     VGFGDQINKD ESYRPIVDYI DAQFENYLQE ELKIRRSLFD YHDTRIHVCL YFITPTGHSL
     KSLDLVTMKK LDSKVNIIPI IAKADTISKS ELHKFKIKIM GELVSNGVQI YQFPTDDETV
     AEINAVMNAH LPFAVVGSTE EVKVGNKLVR ARQYPWGVVQ VENENHCDFV KLREMLIRVN
     MEDLREQTHS RHYELYRRCK LEEMGFQDSD GDSQPFSLQE TYEAKRKEFL SELQRKEEEM
     RQMFVNKVKE TELELKEKER ELHEKFEHLK RVHQEEKRKV EEKRRELEEE TNAFNRRKAA
     VEALQSQALH ATSQQPLRKD KDKKKVPQLK QALLQNTY
//