ID A0A452CM18_BALAS Unreviewed; 748 AA.
AC A0A452CM18;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Lysine-specific demethylase 4C isoform X5 {ECO:0000313|RefSeq:XP_028024051.1};
GN Name=KDM4C {ECO:0000313|RefSeq:XP_028024051.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028024051.1};
RN [1] {ECO:0000313|RefSeq:XP_028024051.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028024051.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_028024051.1; XM_028168250.1.
DR AlphaFoldDB; A0A452CM18; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd20465; Tudor_JMJD2C_rpt1; 1.
DR CDD; cd20468; Tudor_JMJD2C_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.10.330.70; -; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR040477; KDM4-like_Tudor.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF18104; Tudor_2; 2.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 444..557
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 66..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 84280 MW; 689C645E0EFE319B CRC64;
MVKCTCRKDM VKISMDIFVR KFQPDRYQLW KQGKDIYTID HTKPTPESTP EVKAWLQRRR
KVRKASRSFQ CTSSHSKRPK NEEDEEVSAA VDVSCPTPDP DPDELKDSEK PEEAVKLANT
EAPSEEEASA SRMQLDHNLS DNIRFAGNVC LSTSVAEKIK TEADQTCATI PPSIPSDADD
SMSSGHVLSK ESEPPKLPWP KSPESCSSVV ESNSALTEGE ESDVESHGVG LEPGEVPEVP
SGERNGFKVP SRLEGETKTA KSWRHPLSKP PARSPMTLVK QQATSDEELP EVPSIEEEVE
ETESWAKPLV HLWQTKSPNF VAEQEYNAAM GRMEPYCAIC ALLMPYYKPD SSNEENDSRW
ETKLDEVVTS GGKTKPLIPE MCFIYSEENI EYSPPNAFLE EDGTSLLISC AKCRVRVHAS
CYGIPSHEIC DGWLCARCKR NAWTAECCLC NLRGGALKET KNNKWAHVMC AVAVPEVRFT
NVPERTQIDV GRIPLQRLKL KCMFCRHRVK KVSGACIQCS YGRCPASFHV TCAHAAGVLM
EPDDWPYVVN ITCFRHKVNP NVKSKAGEKG IAVGQTVITK HRNTRYYSCR VIAVTAQTFY
EVVFDDGSFS RDTFPEDIVS RDCVKLGPPA EGEVVQVKWP DGKLYGAKYL GSNVAHMYQV
EFEDGSQIAM KREDIYTLDE ELPKRVKARF STASDMRFED TFYGTDIIQG EKKRQRVLSS
RFKNEYVDDP VYRTFLKSSF QKKCQKRQ
//
