ID   A0A452CND6_BALAS        Unreviewed;      1210 AA.
AC   A0A452CND6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=LOW QUALITY PROTEIN: limbin {ECO:0000313|RefSeq:XP_028024527.1};
GN   Name=EVC2 {ECO:0000313|RefSeq:XP_028024527.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028024527.1};
RN   [1] {ECO:0000313|RefSeq:XP_028024527.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028024527.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC       {ECO:0000256|ARBA:ARBA00004309}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004370}.
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DR   RefSeq; XP_028024527.1; XM_028168726.1.
DR   STRING; 310752.A0A452CND6; -.
DR   InParanoid; A0A452CND6; -.
DR   OrthoDB; 4261679at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:InterPro.
DR   InterPro; IPR022076; Limbin.
DR   InterPro; IPR026501; Limbin/EVC.
DR   PANTHER; PTHR16795:SF14; LIMBIN; 1.
DR   PANTHER; PTHR16795; LIMBIN/ELLIS-VAN CREVELD PROTEIN; 1.
DR   Pfam; PF12297; EVC2_like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        197..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1064..1083
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          334..390
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          607..634
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1210 AA;  138012 MW;  CBE573F5D340CCA2 CRC64;
     MKFNKKTEVF NPPPTSAASS GPWIHSVFAF IPSWPKKTLF KRESAVTHHL YGDISRDIQG
     TSENGVIFQK CAVVSVQSEW PTAHVRLFVN NTRTPAATNL SDLLLLDNIT GLTVRESAGN
     QTSRGFQAFR KKFLQVGDSF SVSYTASLEA RDVGSGEVLM LPAQLSFQSS SPNRAQLKAL
     FTITTEEKIT VLPNHGLHAA GFFVAFILSL VLTWAVLFFM VRYQCLKGSV LTRHQVQHHE
     SKLERSQFTS ADGVNEDLAL NDQMIDILSS EDPGSMLQAL EELEIATLNR ADSDLEACRT
     QISKDIIALL LKNLTSSGHL SPQVERRMGA VFKKQFLLLE KENQEXXXXX XXXXXXXXXX
     XXXXKTESQY QREMAAMEEA EEMLKRVSER SAIECSSLLR TLHGLEQEHL RRSLALQQEE
     DFAKAHRQLA IFQRNELHNI FFTQIKSAIF KGELKPEAAK MLLQDYSKIQ ENVEELMDFF
     QASKRYHLSK RFGHREYLVQ NIQSSETRVQ GLLSTASAQL TLLIQKHERA GYLDEDQMRV
     LLERAQTEVF SIKQKLDNDL KQEKKKLHQK LIIKRRREML QKHKEQRREQ LSVAEAFGAA
     EDARQYMGQW RSLVAEHSAT LEELQERLDQ AALDELRALT LSLSEKATEQ LRRLQNSVMT
     QELLKRGVPW LFLQQILEEH SRDLAARAER LEGEERDRGQ EGIQSVRQRL KDDALEASTE
     EQAELRHWEH LIFMKLWSSA FSLSEEELLG MRQEVHGCFA QMDRSLALPK IRARVLLQQF
     QTAWREAEFL KLDQALAAPE LQPQSKARKP RSKSKSKTDL LKKCTEDKIQ LFEEQAPEDL
     VEKVRGELLR ERVQQLEAQE GRFAESLVSL QFQKAARMAK TLWAYTALLT IQDLLLEELS
     ASETLTKSAC TQILESHSPE LQELERKLED QLAHQEAAQL QRALESRQQW AGEGPGLLHE
     PEEETDSERQ VSAVLRRALS KGQKLLEHHQ QSLREEQENS VMLEDLLENM ETDTFVTLYG
     QELRLASYLS KLTMLPGGTL RWLLSVAVPA ALQPELLSVL DPVGQRHQDH TAESDGGGAQ
     ADLGRRGKHQ GWWQAFESKL RGELISRGLE KMRWAHKRKE SILKKTCPPL RERVIFSGKG
     SWPHLSLESI GELAPVPIVG AETIDLLNTG EKLFIFRNPK EPEISLHLPP RKKKKNFLNA
     KKATWALGMN
//