ID A0A452CPW3_BALAS Unreviewed; 451 AA.
AC A0A452CPW3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Myocyte-specific enhancer factor 2C isoform X6 {ECO:0000313|RefSeq:XP_028025067.1};
GN Name=MEF2C {ECO:0000313|RefSeq:XP_028025067.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_028025067.1};
RN [1] {ECO:0000313|RefSeq:XP_028025067.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028025067.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_028025067.1; XM_028169266.1.
DR AlphaFoldDB; A0A452CPW3; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; Transcription factor, MADS-box; 1.
DR InterPro; IPR022102; HJURP_C.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR PANTHER; PTHR48019:SF109; MYOCYTE-SPECIFIC ENHANCER FACTOR 2A; 1.
DR PANTHER; PTHR48019; SERUM RESPONSE FACTOR HOMOLOG; 1.
DR Pfam; PF12347; HJURP_C; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SRF-like; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000259|PROSITE:PS50066"
FT REGION 92..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 48992 MW; AA37B014EFF0783F CRC64;
MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST
DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSALNK KENKGCESPD
PDSSYALTPR TEEKYKKINE EFDNMIKSHK IPAVPPPNFE MPVSIPVSSH NSLVYSNPVS
SLGNPNLLPL AHPSLQRNSM SPGVTHRPPS AGNTGGLMGG DLTSGAGTSA GNGYGNPRNS
PGLLVSPGNL NKNMQAKSPP PMNLGMNNRK PDLRVLIPPG SKNTMPSVNQ RINNSQSAQS
LATPVVSVAT PTLPGQGMGG YPSAISTTYG NEYSLSSADL SSLSGFNTAS ALHLGSVTGW
QQQHLHNMPP SALSQLGDRT TTPSRYPQHT RHEAGRSPVD SLSSCSSSYD GSDREDHRNE
FHSPIGLTRP SPDERESPSV KRMRLSEGWA T
//
