ID A0A452DK44_BOVIN Unreviewed; 299 AA.
AC A0A452DK44;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Alpha-2-glycoprotein 1, zinc-binding {ECO:0000313|Ensembl:ENSBTAP00000037042.3};
GN Name=AZGP1 {ECO:0000313|Ensembl:ENSBTAP00000037042.3,
GN ECO:0000313|VGNC:VGNC:26367};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000037042.3, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000037042.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000037042.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000037042.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000037042.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
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DR AlphaFoldDB; A0A452DK44; -.
DR SMR; A0A452DK44; -.
DR Ensembl; ENSBTAT00000037204.3; ENSBTAP00000037042.3; ENSBTAG00000026236.3.
DR VEuPathDB; HostDB:ENSBTAG00000026236; -.
DR VGNC; VGNC:26367; AZGP1.
DR GeneTree; ENSGT01100000263517; -.
DR InParanoid; A0A452DK44; -.
DR OMA; APYSCYV; -.
DR Reactome; R-BTA-5223345; Miscellaneous transport and binding events.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000026236; Expressed in oviduct epithelium and 90 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IEA:Ensembl.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR CDD; cd21010; IgC1_MHC-like_ZAG; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR PANTHER; PTHR16675:SF276; ZINC-ALPHA-2-GLYCOPROTEIN; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..299
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019094782"
FT DOMAIN 204..289
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 299 AA; 33842 MW; 7A72D1179A8FD864 CRC64;
MVPVLLALLL LLGPAVSEET QAGNYSLSFL YTGLSKPREG FPSFQAVAYL NDQPFFHYNS
EGRRAEPLAP WSQVEGMEDW EKESALQRAR EDIFMETLSD IMDYYKDREG SHTFQGAFGC
ELRNNESSGA FWGYAYDGQD FIKFDKEIPA WVPLDPAAQN TKRKWEAEAV YVQRAKAYLE
EECPGMLRRY LPYSRTHLDR QESPSVSVTG HAAPGHKRTL KCLAYDFYPR SIGLHWTRAG
DAQEAESGGD VLPSGNGTYQ SWVVVGVPSE DQAPYSCHVE HRSLTRPLTV PWDPRQQAE
//
