ID A0A452DQ36_CAPHI Unreviewed; 93 AA.
AC A0A452DQ36;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=C-C motif chemokine {ECO:0000256|RuleBase:RU361150};
GN Name=LOC108638246 {ECO:0000313|Ensembl:ENSCHIP00000001848.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000001848.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000001848.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000001848.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361150}.
CC -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC {ECO:0000256|ARBA:ARBA00010868, ECO:0000256|RuleBase:RU361150}.
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DR EMBL; LWLT01000022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017919705.1; XM_018064216.1.
DR AlphaFoldDB; A0A452DQ36; -.
DR SMR; A0A452DQ36; -.
DR STRING; 9925.ENSCHIP00000001848; -.
DR Ensembl; ENSCHIT00000005180.1; ENSCHIP00000001848.1; ENSCHIG00000003747.1.
DR GeneID; 108638246; -.
DR KEGG; chx:108638246; -.
DR GeneTree; ENSGT01100000263482; -.
DR OMA; WVQALLE; -.
DR OrthoDB; 4265193at2759; -.
DR Proteomes; UP000291000; Chromosome 19.
DR Bgee; ENSCHIG00000003747; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00272; Chemokine_CC; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR000827; Chemokine_CC_CS.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF180; C-C MOTIF CHEMOKINE; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
DR PROSITE; PS00472; SMALL_CYTOKINES_CC; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|RuleBase:RU361150};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU361150};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Secreted {ECO:0000256|RuleBase:RU361150};
KW Signal {ECO:0000256|RuleBase:RU361150}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT CHAIN 25..93
FT /note="C-C motif chemokine"
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT /id="PRO_5018824003"
FT DOMAIN 31..89
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
SQ SEQUENCE 93 AA; 10132 MW; 14DA85437B95E038 CRC64;
MEVPGAALAV LLLTAALSAH TCSATLGANT PTACCFSFVS RQIPRKFVDD YYETSSQCSK
PGVIFKTKRG RQVCADPSED WVQEYITDLE LNP
//
