ID   A0A452DVW3_CAPHI        Unreviewed;       523 AA.
AC   A0A452DVW3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Glycerate kinase {ECO:0000256|ARBA:ARBA00020720};
DE            EC=2.7.1.31 {ECO:0000256|ARBA:ARBA00012101};
GN   Name=GLYCTK {ECO:0000313|Ensembl:ENSCHIP00000003916.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000003916.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000003916.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000003916.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31; Evidence={ECO:0000256|ARBA:ARBA00000694};
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-2 family.
CC       {ECO:0000256|ARBA:ARBA00005393}.
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DR   EMBL; LWLT01000024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005695938.2; XM_005695881.3.
DR   RefSeq; XP_017922425.1; XM_018066936.1.
DR   AlphaFoldDB; A0A452DVW3; -.
DR   STRING; 9925.ENSCHIP00000003916; -.
DR   Ensembl; ENSCHIT00000011191.1; ENSCHIP00000003916.1; ENSCHIG00000008125.1.
DR   GeneID; 102183921; -.
DR   KEGG; chx:102183921; -.
DR   CTD; 132158; -.
DR   GeneTree; ENSGT00390000014365; -.
DR   OMA; GKAAWRM; -.
DR   OrthoDB; 5404098at2759; -.
DR   Proteomes; UP000291000; Chromosome 22.
DR   Bgee; ENSCHIG00000008125; Expressed in liver and 18 other cell types or tissues.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.10180; Glycerate kinase, MOFRL-like N-terminal domain; 1.
DR   Gene3D; 3.40.1480.10; MOFRL domain; 1.
DR   InterPro; IPR037035; GK-like_C_sf.
DR   InterPro; IPR038614; GK_N_sf.
DR   InterPro; IPR007835; MOFRL.
DR   InterPro; IPR025286; MOFRL_assoc_dom.
DR   InterPro; IPR039760; MOFRL_protein.
DR   PANTHER; PTHR12227; GLYCERATE KINASE; 1.
DR   PANTHER; PTHR12227:SF0; GLYCERATE KINASE; 1.
DR   Pfam; PF13660; DUF4147; 1.
DR   Pfam; PF05161; MOFRL; 1.
DR   SUPFAM; SSF82544; GckA/TtuD-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   DOMAIN          38..288
FT                   /note="MOFRL-associated"
FT                   /evidence="ECO:0000259|Pfam:PF13660"
FT   DOMAIN          402..514
FT                   /note="MOFRL"
FT                   /evidence="ECO:0000259|Pfam:PF05161"
SQ   SEQUENCE   523 AA;  54768 MW;  FDEA382A252176BA CRC64;
     MAAALQVLRH LARAPSGPLL LGGPLARLAS SMALAEQARQ LFESAVGAVL PGPMLQRALS
     LDPDSGELKV RDRSFQLRQN LYLVGFGKAV LGMAATAEEL LGQHLVQGVI SVPKGIRAAM
     EHAGKQEMLL KPHSCIQVFE GAEDNLPDRD ALRAALAIRQ LAEGLTADDL LLVLISGGGS
     ALLPAPIPPV TLEEKQTLTK LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI
     LSDVVGDPVE VIASGPTVAS IHSVQDCLHI LNRYGLRTAL PRSVKTVLAR ADSDPHGPHT
     CGHVLNVILG SNALALAEAQ RQAEALGYRA VVLSTAIQGD VKSVAQFYGL LARVAGARLA
     LPGPGASVEE DERLCELAAD LQLPDLQLKE ALEAVVGARG PVCLLAGGEP TVQLQGSGKG
     GRNQELALRV GVELRQWPLG TVDVLFLSGG TDGQDGPTEA AGAWVRPELT SQAAAEGLDV
     ATFLAHNDSH TFFCRFQGGA HLLYTGLTGT NVMDAHFLFL HPQ
//